2015―2019年度合肥市流感样症状病例流行病学的特征分析  

Analysis of epidemic and etiological characteristics of influenza-like cases in Hefei City from 2015 to 2020

作　　者：李迎庆 刘旭祥[2] 赵科伕[2] 胡成洋 张康娣 程馨 王杰 虞文杰 王新强 侯赛[4] 张秀军[1] LI Ying-qing;LIU Xu-xiang;ZHAO Ke-fu;HU Cheng-yang;ZHANG Kang-di;CHENG Xin;WANG Jie;YU Wen-jie;WANG Xin-qiang;HOU Sai;ZHANG Xiu-jun(Department of Epidemiology and Health Statistics,School of Public Health,Anhui Medical University,Hefei 230032,China;Health Emergency Office,Hefei Center for Disease Control and Prevention,Hefei 230061,China;Department of Humanities and Medicine,School of Humanities and Medicine,Anhui Medical University,Hefei 230032,China;Department of Health Emergency Management and Acute Infections Diseases Prevention,Anhui Province Center for Disease Control and Prevention,Hefei 230061,China)

机构地区：[1]安徽医科大学公共卫生学院流行病与卫生统计学系,合肥230032 [2]合肥市疾病预防控制中心卫生应急办公室,合肥230061 [3]安徽医科大学人文医学学院人文医学系,合肥230032 [4]安徽省疾病预防控制中心卫生应急管理与急性传染病防治科,合肥230061

出　　处：《中华疾病控制杂志》2021年第12期1453-1458,共6页Chinese Journal of Disease Control & Prevention

基　　金：国家自然科学基金(82073565);安徽省自然科学基金(2008085MH263)。

摘　　要：目的掌握合肥市2015―2019年度流行性感冒(简称流感)活动水平及流行动态,为今后流感防控提供科学依据。方法从"中国流感监测信息系统"收集2015―2019年度合肥市哨点医院每日流感样病例(influenza like illness,ILI)数据以及相应的病原学检测结果,分析其流行情况。结果 2015―2019年度,合肥市3家哨点医院监测ILI累计183 789例,占门/急诊人数的5.06%。ILI发病率有明显的季节性,发病高峰主要在每年的11月至次年4月,各年度ILI发病率差异有统计学意义(χ^(2)=484.793,P<0.001)。实验室共接收样本17 442份,检测结果阳性4 925份,占28.24%,高阳性率集中在12月至次年4月,不同月份阳性率差异有统计学意义(χ^(2)=2 567.306,P<0.001)。从分型上看,主要为Victoria型和季H3型。ILI发病率和病原学阳性率之间呈正相关(r=0.491,P=0.021)。结论 2015―2019年度合肥市流感活动呈现冬季和夏季2个高峰,不同流感病毒亚型混合流行。Objective To explore the activity level and epidemic dynamics of influenza in Hefei City from 2015 to 2019,and to provide scientific basis for the prevention and control of influenza in the future.Methods Data of daily influenza-like illness(ILI) cases and corresponding etiological surveillance information were collected from "China Influenza Surveillance Information System" to analyze the influenza epidemic from 2015 to 2019 in Hefei City.Results A total of 183 789 ILI cases were reported in 3 sentinel hospitals in Hefei City from 2015 to 2019,accounting for 5.06% of the total number of outpatients visits and emergency departments visits.The peak of ILI cases was mainly from November of the current year to April of the following year,and the difference of positive rate in different months was statistically difference(χ^(2)=484.793,P<0.001).The laboratory received a total of 17 442 samples,of which 4 925 were positive,which accounting for 28.24% of the total number of samples submitted for inspection.The high positive rate was from December to April of the following year,and there was statistically different in different months(χ^(2)=2 567.306,P<0.001).Besides,the main subtype of influenza viruses was Victoria and H3 types.There was a positive correlation between the prevalence of ILI and the positive rate of etiology(r=0.491,P=0.021).Conclusions The influenza epidemic peaked in winter and summer from 2015 to 2019,and there was a mixed epidemic of influenza virus subtypes.

关 键 词：流感 流感样病例 流感监测 

分 类 号：R181.3[医药卫生—流行病学] R511.7[医药卫生—公共卫生与预防医学]