新型冠状病毒对心血管系统影响的研究进展  

Research progess in effect of novel coronavirus on cardiovascular system

作　　者：李雷[1] 彭祎雪 张洁[1] 卓利佳 赵霞[1] 张龙浩[2] 朱培嘉 曾国军[4] LI Lei;PENG Yixue;ZHANG Jie;ZHUO Lijia;ZHAO Xia;ZHANG Longhao;ZHU Peijia;ZENG Guojun(Department of Clinical Research Management,West China Hospital,Sichuan University,Chengdu,610041,P.R.China;Double First-class Construction Office,West China Hospital,Sichuan University,Chengdu,610041,P.R.China;Department of Science and Technology,West China Hospital,Sichuan University,Chengdu,610041,P.R.China;Department of Vascular Surgery,West China Hospital,Sichuan University,Chengdu,610041,P.R.China)

机构地区：[1]四川大学华西医院临床研究管理部,成都610041 [2]四川大学华西医院“双一流”建设办公室,成都610041 [3]四川大学华西医院科技部,成都610041 [4]四川大学华西医院血管外科,成都610041

出　　处：《中国胸心血管外科临床杂志》2022年第1期106-113,共8页Chinese Journal of Clinical Thoracic and Cardiovascular Surgery

基　　金：四川省科技厅重大项目(2018SZ0353);四川大学华西医院新型冠状病毒肺炎疫情科技攻关项目(HX-2019-n Co V-035)。

摘　　要：新型冠状病毒肺炎(COVID-19)患者存在心血管系统受损的临床表现,且此类患者进展为重症或死亡的风险较高。目前尚不清楚新型冠状病毒对心血管系统的影响机制。本文重点介绍新型冠状病毒与心血管系统疾病的相互关系,总结新型冠状病毒损伤心血管系统可能的机制,包括病毒直接损害心肌细胞及其传导系统,细胞因子风暴,氧供需失衡,药物影响,应激等对心血管系统的损害,并总结其临床表现、治疗方法等。In addition to the typical respiratory symptoms,COVID-19 patients present with clinical manifestations of cardiovascular system damage,and they are at higher risk of intensive care or mortality.The mechanism of COVID-19’s impact on the cardiovascular system is still unclear,therefore we need to pay close attention to it.Based on the existing research,this paper focused on the concurrent characteristics of the cardiovascular system diseases,summarized the possible mechanisms of cardiovascular system damage,including the coronavirus invaders directly into cardiomyocytes and its conduction system,with complications or accompanying conditions such as cytokine storm,imbalance of oxygen supply and demand,drug influence,stress and other damage to cardiovascular system.Meanwhile,current clinical manifestations and treatment methods of COVID-19 were summarized.

关 键 词：新型冠状病毒 新型冠状病毒肺炎 心血管系统 综述 

分 类 号：R563.1[医药卫生—呼吸系统] R54[医药卫生—内科学]