新生儿先天性心脏病筛查技术的现状及智能化发展趋势  

Current status and intelligent development trend of the screening technology for neonatal congenital heart disease

作　　者：胡晓静[1] 王春宇(综述) 张成强[1,4] 贾品[1] 黄国英(审校)[1,5,6,7] HU Xiao-jing;WANG Chun-yu;ZHANG Cheng-qiang;JIA Pin;HUANG Guo-ying(National Children’s Medical Center/Children’s Hospital,Fudan University,Shanghai 201102,China;Beijing Sunwise Information Technology Corporation,Beijing 100190,China;Beijing Institute of Control Engineering,Beijing 100190,China;Obstetrics&Gynecology Hospital,Fudan University,Shanghai 200011,China;Shanghai Key Laboratory of Birth Defects,Shanghai 201102,China)

机构地区：[1]国家儿童医学中心/复旦大学附属儿科医院,上海201102 [2]北京轩宇信息技术有限公司,北京100190 [3]北京控制工程研究所,北京100190 [4]复旦大学附属妇产科医院,上海200011 [5]上海市出生缺陷防治重点实验室,上海201102 [6]中国儿科医师分会 [7]中华儿科学会

出　　处：《复旦学报（医学版）》2022年第1期107-113,共7页Fudan University Journal of Medical Sciences

基　　金：国家重点研发计划(2016YFC1000500);复旦大学附属儿科医院产学研高新技术转化孵化项目(FDEKCXY02)。

摘　　要：先天性心脏病(先心病)是我国最常见的先天畸形。"双指标"方案(脉氧测定结合心脏杂音听诊)已在全国推广。目前,脉氧测定已有较多商用设备,但在低灌注、抗干扰、双指标集成等方面仍存在不足;而心脏杂音听诊目前多由检查者通过听诊器进行判断,受主观因素影响较大;而近年来出现的智能听诊技术在实用性、一致性、敏感性和数据库方面尚存在不足,不能直接用于新生儿心杂音智能识别,且缺乏成熟商用产品。因此,"双指标"方案推广过程中集成化、自动化、智能化、同质化的程度较低,影响了新生儿先心病筛查效率和准确性。本文综述了新生儿先心病筛查技术的现状和智能化发展趋势以及课题组自主研发双指标智能筛查仪的进展情况。Congenital heart disease(CHD)is the most common congenital malformation in China.The dual-index screening method(i.e.pulse oximetry plus cardiac murmur auscultation)has been promoted nationwide in China.At present,pulse oximetry has many commercial equipments,but there are shortcomings in low perfusion,anti-interference and dual-index integration.Meanwhile,the auscultation of cardiac murmur is mostly judged by examiner through the stethoscope so far,which is greatly affected by subjective factors.However,the intelligent ausculation technology introduced in recent years has defects in practicability,consistency,precision and database and can’t be applied to cogenital cardiac murmur ausculation directly.Besides,related matured commercial products are also lack.Therefore,the degree of integration,automation,intelligence and homogenization in the process of promotion of the“dual-index method”is low,which affects the efficiency and accuracy of neonatal CHD screening.This paper reviews the current situation and intelligent trend of the screening technology for neonatal CHD,as well as the progress of the dual-index intelligent CHD screening device developed by our research group.

关 键 词：先心病 双指标 血氧饱和度 心脏杂音 智能筛查 

分 类 号：R722.1[医药卫生—儿科]