极短时心率变异性与脉率变异性指标一致性的分析  

Analysis on the consistency of extremely short-term heart rate variability and pulse rate variability

作　　者：彭敏 何宝林 刘静[3] 于璐 PENG Min;HE Baolin;LIU Jing;YU Lu(Department of Biomedical Engineering,School of Fundamental Sciences,China Medical University,Shenyang 110122,China;State Key Laboratory of Experimental Hematology,National Clinical Research Center for Blood Diseases,Institute of Hematology&Blood Diseases Hospital,Chinese Academy of Medical Sciences&Peking Union Medical College,Tianjin 300020,China;Department of Nuclear Medicine,Zhongnan Hospital of Wuhan University,Wuhan 430071,China)

机构地区：[1]中国医科大学公共基础学院生物医学工程系,沈阳110122 [2]中国医学科学院血液病医院(中国医学科学院血液学研究所)实验血液学国家重点实验室国家血液病临床医学研究中心,天津300020 [3]武汉大学中南医院核医学科,武汉430071

出　　处：《生物医学工程研究》2021年第4期360-365,共6页Journal Of Biomedical Engineering Research

基　　金：国家自然科学基金资助项目(81401485)。

摘　　要：本研究利用多导睡眠仪采集呼吸暂停、快速呼吸、慢速呼吸和平静呼吸四种状态下的心电、脉搏信号,来进行极短时15 s的心率变异性与脉率变异性六个指标计算。通过Bland-Altman一致性分析图与散点图、单样本K-S检验、Mann-Whitney U检验、Pearson相关性系数来比较心率与脉率的一致性程度,结果显示,MEAN,Lomb-nLF,Lomb-nHF,Lomb-nLF/nHF,DFA1五个指标在四个状态下具有较好的一致性。因此,可以用极短时内的脉率变异性来替代心率变异性,以反映自主神经功能变化。We used the polysomnography to collect the electrocardiogram and Oxygen saturation of four breathing states(apnea,fast breathing,slow breathing,calm breathing)to perform heart rate variability and pulse rate variability for a very short 15 s index calculation.Through the Bland-Altman consistency analysis chart and scatter plot,one-sample K-S test,Mann-Whitney U test,Pearson correlation coefficient,the consistency of heart rate and pulse rate was compared.The results showed that the five indicators of MEAN,Lomb-nLF,Lomb-nHF,Lomb-nLF/nHF,and DFA1 had good consistency in the four states.The extremely short-term pulse rate variability can to replace heart rate variability to reflect the changes of autonomic nerve function.

关 键 词：极短时 一致性分析 心率变异性 脉率变异性 睡眠呼吸暂停 自主神经系统 

分 类 号：R318[医药卫生—生物医学工程] R332[医药卫生—基础医学]