骨质疏松参与退行性脊柱侧凸发病的研究现状  

Osteoporosis involved in the pathogenesis of degenerative scoliosis:research status

作　　者：段煜东 张子程 李博[1] 程亚军[1] 陈绍丰 李明[1] 周潇逸[1] 魏显招[1] DUAN Yu-dong;ZHANG Zi-cheng;LI Bo;CHENG Ya-jun;CHEN Shao-feng;LI Ming;ZHOU Xiao-yi;WEI Xian-zhao(Department of Orthopaedics,Changhai Hospital,Naval Medical University(Second Military Medical University),Shanghai 200433,China)

机构地区：[1]海军军医大学(第二军医大学)长海医院骨科,上海200433

出　　处：《第二军医大学学报》2021年第12期1402-1407,共6页Academic Journal of Second Military Medical University

基　　金：国家自然科学基金(81900809);上海市卫生健康委员会卫生行业临床研究专项(20194Y0232);上海市卫生系统优秀人才培养计划(2018YQ26)。

摘　　要：退行性脊柱侧凸和骨质疏松的患者都主要集中于老年人群,且两者均可导致严重的脊柱病变。早期研究发现骨质疏松可能在椎体不对称性退变和躯干肌力下降等方面参与退行性脊柱侧凸的发病,但也有少数研究表明两者在致病机制上无明显联系。本文就此对骨质疏松如何参与退行性脊柱侧凸发病进行综述,旨在进一步明确骨质疏松是否会对患者脊柱产生影响,从而为预防和治疗退变性脊柱侧凸提供思路。Degenerative scoliosis and osteoporosis mainly occurr in the elderly,and both can lead to serious spinal lesions.Early studies have found that osteoporosis may participate in the pathogenesis of degenerative scoliosis involving vertebral body asymmetric degeneration and decreased trunk muscle strength;however,a few studies have shown that there is no obvious relationship between them.This article reviews how osteoporosis participates in the pathogenesis of degenerative scoliosis,aiming to further clarify whether osteoporosis has an impact on the spine of patients,so as to provide evidence for the prevention and treatment of degenerative scoliosis.

关 键 词：退行性脊柱侧凸 骨质疏松 骨结构 骨密度 肌肉强度 

分 类 号：R682.3[医药卫生—骨科学]