艾司洛尔联合胺碘酮治疗老年室性心律失常临床效果与安全性分析  

Clinical Effect and Safety Analysis of Esmolol Combined with Amiodarone in the Treatment of Senile Ventricular Arrhythmia

作　　者：陶世鹏 TAO Shipeng(The Third People's Hospital of Liaoyang,Liaoyang 111000,China)

机构地区：[1]辽宁省辽阳市第三人民医院,辽宁辽阳111000

出　　处：《中国医药指南》2022年第4期13-16,共4页Guide of China Medicine

摘　　要：目的评价艾司洛尔和胺碘酮联合用药方式治疗老年室性心律失常的临床效果和安全性。方法将2018年1月至2019年8月在我院治疗的58例室性心律失常患者按照随机方法分为观察组和对照组,每组29例。观察组行艾司洛尔联合胺碘酮治疗,对照组行常规胺碘酮治疗,分别计算两组相关数据统计结果,并做统计学比较。结果①经统计,观察组治疗有效率为96.55%(28/29),对照组为72.41%(21/29),有统计学差异(P<0.05)。②观察组患者的1个月内,复发率和并发症发生率都普遍低于对照组,有统计学差异(P<0.05)。③治疗前两组患者的心电图指标无统计学意义(P>0.05),治疗后两组QTcd与心率水平和治疗前相比均有改善,但观察组患者的改善效果比对照组更优,有统计学差异(P<0.05)。④治疗前,两组患者的左心室射血分数、左心室舒张末期容积、左心室收缩末期容积等无统计学差异(P>0.05),治疗之后,两组患者的左心室射血分数、左心室舒张末期容积、左心室收缩末期容积等均得到改善,但观察组患者的改善效果更好,有统计学差异(P<0.05)。⑤观察组患者治疗之后的收缩压和舒张压水平改善效果比对照组更好,有统计学差异(P<0.05)。结论对老年室性心律失常患者应用艾司洛尔联合胺碘酮的疗法比常规单一胺碘酮治疗效果更好,能够调整患者心电图指标,增强患者心功能,还可优化患者血压水平,减少患者复发率,获得具有较好的安全性,可改善临床指标,值得推广。Objective To evaluate the clinical efficacy and safety of esmolol and amiodarone in the treatment of ventricular arrhythmia in the elderly.Methods Fifty-eight patients with ventricular arrhythmia who were treated from January 2018 to August 2019 in my hospital were randomly divided into observation group and control group,with 29 cases in each group.The observation group was treated with esmolol combined with amiodarone,and the control group was treated with conventional amiodarone.The statistical results of the two groups were calculated and statistically compared.Results(1)According to statistics,the effective rate of treatment in the observation group was 96.55%(28/29),and the control group was 72.41%(21/29).There was a statistical difference(P<0.05).(2)One of the patients in the observation group Within months,the recurrence rate and complication rate were generally lower than those of the control group,with statistical differences(P<0.05).(3)The ECG indicators of the two groups of patients before treatment were not statistically significant(P>0.05),after treatment the QTcd of the two groups was improved compared with the heart rate level and before treatment,but the improvement effect of the observation group was better than that of the control group,and there was a statistical difference(P<0.05).(4)Before treatment,the left ventricle of the two groups of patients There was no significant difference in ejection fraction,left ventricular end-diastolic volume,left ventricular end-systolic volume,etc.(P>0.05).After treatment,left ventricular ejection fraction,left ventricular end-diastolic volume,and left ventricular end-systolic volume of the two groups of patients Equally improved,but the improvement effect of patients in the observation group was better,with a statistical difference(P<0.05).(5)The improvement effect of systolic and diastolic blood pressure levels in the observation group after treatment was better than that of the control group,with statistics Academic difference(P<0.05).Conclusion The effec

关 键 词：艾司洛尔 胺碘酮 老年室性心律失常 

分 类 号：R541.7[医药卫生—心血管疾病]