AiPlan放射治疗计划系统的临床剂量学测试  

Clinical Dosimetric Testing of the AiPlan Radiotherapy Treatment Planning System

作　　者：廖雄飞[1,2,3,4] 袁珂 徐鹏[1,2,3,4] 李厨荣 刘敏[1,2,3,4] 吴骏翔 黎杰[1,2,3,4] LIAO Xiongfei;YUAN Ke;XU Peng;LI Churong;LIU Min;WU Junxiang;LI Jie(Research Institute of Sichuan Cancer Hospital;Sichuan Cancer Prevention and Treatment Center;School of Medicine,University of Electronic Science and Technology of China;Sichuan Provincial Key Laboratory of Radiation Oncology,Sichuan Chengdu 610041,China)

机构地区：[1]四川省肿瘤医院研究所 [2]四川省癌症防治中心 [3]电子科技大学医学院 [4]放射肿瘤学四川省重点实验室,四川成都610041

出　　处：《中国医疗设备》2022年第1期171-173,共3页China Medical Devices

基　　金：四川省科技计划资助(2021YFG0320)。

摘　　要：目的对AiPlan三维放射治疗计划系统(Treatment Planning System,TPS)进行临床剂量学验证,以检验AiPlan系统在临床正常使用条件下的有效性和安全性。方法随机选取60例在Pinnacle计划系统上已完成放射治疗计划设计的患者,将60例患者的CT图像及RT Structures通过DICOM网络传输至AiPlanTPS,并应用AiPlan系统对60例临床病例重新进行放射治疗计划设计。分别对Pinnacle和AiPan两组放射治疗计划进行绝对点剂量以及二维面剂量验证,同时比较两组放射治疗计划等中心及附近层面剂量分布情况,运用统计学方法对两组计划剂量验证结果进行分析。结果 AiPlanTPS能够实现逆向调强放射治疗计划设计所需的各项功能;经AiPlan系统设计的60例放射治疗计划均能满足临床剂量要求;绝对点剂量误差范围为-3.27%~3.98%,二维面剂量验证Gamma通过率为97.5%±2.8%,该结果与Pinnacle系统计划验证结果相比无统计学差异(t=0.149、1.858,P=0.882、0.068)。结论 Aiplan三维TPS在剂量计算精度上达同类进口产品相似水平,能够满足临床要求。Objective Clinical dosimetry verification of AiPlan 3 D radiotherapy planning system was carried out to investigate the safety and validity of AiPlan 3-D radiotherapy treatment planning system(TPS). Methods A total of 60 patients who had completed the radiotherapy planning design on Pinnacle Treatment planning system were randomly selected.The CT images and RT Structures of the 60 patients were transmitted to AiPlan Treatment planning system through DICOM. And the AiPlan system was used to redesign the radiation plan for 60 clinical cases. The absolute dose and two-dimensional dose of Pinnacle and AiPlan groups were verified respectively, and their dose verification results were compared. Meanwhile, Dose distribution at the center and near the radiation plan was compared between the two groups, and the results of planned dose verification of the two groups were analyzed by statistical method. Results The AiPlan radiotherapy planning system was capable of implementing the functions required for the design of the reverse intensity modulated radiotherapy plan. All the 60 radiotherapy plans designed by AiPlan TPS could meet the clinical dose requirements. The absolute point dose error range was-3.27%~3.98%, and the Gamma pass rate was 97.5%±2.8% for 2-D dose verification, which showed no statistical difference compared with the results of Pinnacle TPS(t=0.149, 1.858;P=0.882,P=0.068). Conclusion AiPlan TPS is upto the similar level of the imported equipment in terms of dose calculation performance,which can meet the clinical requirements.

关 键 词：放射治疗计划系统 剂量验证 剂量学 

分 类 号：R473.73[医药卫生—护理学]