SRS MapCHECK与EDOSE在立体定向放疗计划剂量验证中的对比  

Comparison of dose verification by SRS MapCHECK versus EDOSE for stereotactic radiotherapy

作　　者：袁玲 刘颖[1] 徐瑶瑶 张红利 张晓鹏 王鑫[1] 石兴源[1] YUAN Ling;LIU Ying;XU Yaoyao;ZHANG Hongli;ZHANG Xiaopeng;WANG Xin;SHI Xingyuan(Department of Radiotherapy,the Fifth Affiliated Hospital of Guangzhou Medical University,Guangzhou 510700,China)

机构地区：[1]广州医科大学附属第五医院放疗科,广东广州510700

出　　处：《中国医学物理学杂志》2022年第1期23-27,共5页Chinese Journal of Medical Physics

基　　金：广州市科技计划项目(201905010004)。

摘　　要：目的:使用SRS MapCHECK和EDOSE对立体定向放疗(SRT)计划进行剂量验证,并比较它们的验证结果。方法:首先比较两种系统在不同方野(2 cm×2 cm、4 cm×4 cm、6 cm×6 cm、10 cm×10 cm)的γ通过率(3%/3 mm),然后选择29例SRT计划,分析两种系统在不同γ标准下的绝对剂量通过率,最后分析EDOSE建立的4种不同物理模型对SRT计划剂量验证的影响。结果:SRS MapCHECK在所有方野和29例SRT计划的绝对剂量γ通过率均高于EDOSE,两者的验证结果有统计学差异(P<0.05);SRS MapCHECK及EDOSE在29例SRT计划的γ通过率(2%/2 mm)分别是为98.60%±2.14%和96.53%±2.41%。基于EDOSE的不同物理模型验证结果有统计学差异,平均γ通过率(2%/2 mm)偏差为1.8%~5.1%。结论:SRS MapCHECK和EDOSE系统均满足SRT计划剂量验证的要求,且SRS MapCHECK的剂量验证通过率优于EDOSE;不同的EDOSE物理模型对SRT计划剂量验证有影响。Objective To carry out dose verification for stereotactic radiotherapy(SRT)using SRS MapCHECK and EDOSE,and to compare the results of dose verification between SRS MapCHECK and EDOSE.Methods The gamma passing rate(3%/3 mm)for different square fields(2 cm×2 cm,4 cm×4 cm,6 cm×6 cm,10 cm×10 cm)using SRS MapCHECK and EDOSE for dose verification were compared,and then,29 SRT plan were selected to analyze the absolute dose passing rate between SRS MapCHECK and EDOSE at different gamma criteria.Finally,the effects of 4 different physical models established in EDOSE system on the dose verification for SRT plan were analyzed.Results The gamma passing rates of absolute dose obtained by SRS MapCHECK in all square fields and 29 cases of SRT plan were higher those of EDOSE,and the verification results between two systems were statistically different(P<0.05).The gamma passing rates(2%/2 mm)of SRS MapCHECK and EDOSE for 29 cases of SRT plan were 98.60%±2.14% and 96.53%±2.41%,respectively.The verification results among different EDOSE physical models were statistically different,and the deviation of average gamma passing rate(2%/2 mm)was 1.8%-5.1%.Conclusion Both SRS MapCHECK and EDOSE satisfy the requirements of dose verification for SRT plan,but the passing rate of dose verification of SRS MapCHECK is higher than that of EDOSE.The dose verification for SRT plan can be affected by different EDOSE physical models.

关 键 词：立体定向放疗 SRS MapCHECK EDOSE γ通过率 剂量验证 

分 类 号：R811.1[医药卫生—放射医学]