乳腺断层摄影合成技术的临床价值  

Clinical value of synthesis technique for mammography

作　　者：孙晓琪 蔡思清[1] 林舒婷 陈倩倩 SUN Xiaoqi;CAI Siqing;LIN Shuting;CHEN Qianqian(Department of Radiology,the Second Affiliated Hospital of Fujian Medical University,Quanzhou 362000,China)

机构地区：[1]福建医科大学附属第二医院放射科,福建泉州362000

出　　处：《中国医学物理学杂志》2022年第1期51-56,共6页Chinese Journal of Medical Physics

基　　金：福建省自然科学基金(2021J01257);吴阶平医学基金(3206750.2021-06-35)。

摘　　要：目的:探讨数字乳腺断层合成X线成像(DBT)结合合成2D图像(SM)对乳腺微钙化的检出和诊断效能。方法:回顾性分析228例乳腺影像及病理资料。3名影像医师独立阅读DBT结合全视野数字化乳腺摄影(FFDM)、DBT结合SM、FFDM、SM 4种模式下影像资料,记录微钙化有无,根据BI-RADS 2013版对微钙化进行分类,分析不同密度乳腺类型中良、恶性微钙化的检出率及诊断效能。结果:不管在致密型乳腺或所有腺体类型乳腺中,4种阅片模式对微钙化检出敏感度的差异无统计学意义(P>0.05),特异度均为100%。DBT结合SM与DBT结合FFDM对微钙化诊断敏感度、特异度及ROC曲线下面积的差异无统计学意义(P>0.05);FFDM的敏感度高于SM,特异度低于SM,ROC曲线下面积高于SM,差异均具有统计学意义(P<0.05)。结论:DBT结合SM与DBT结合FFDM对乳腺微钙化的检出、诊断效能相似。Objective To investigate the detection rate of digital breast tomosynthesis(DBT)combined with synthetic 2 D mammography(SM)for microcalcifications and to disscuss the diagnostic efficiency.Methods The breast imaging and pathological data of 228 cases were analyzed retrospectively.Three radiologists independently interpreted the imaging data in4 different reading modes,including DBT combined with full-field digital mammography(FFDM),DBT combined with SM,FFDM,and SM,and recorded the presence of microcalcifications or not.Finally,the microcalcifications was classified according to BI-RADS 2013.The detection rates of benign and malignant microcalcifications in different mammary glands and the diagnostic performances were analyzed.Results For either dense mammary gland or all types of mammary glands,there was no significant difference in the detection sensitivity of different reading modes to microcalcifications(P>0.05),and the specificity was 100%.No significant difference was found in diagnostic sensitivity,specificity and the area under ROC curve between DBT combined with SM and DBT combined with FFDM(P>0.05).The diagnostic sensitivity and the area under ROC curve of FFDM were higher than those of SM,but the specificity was lower than SM(all P<0.05).Conclusion DBT combined with SM and DBT combined with FFDM have similar performances in microcalcifications detection and diagnostic efficiency.

关 键 词：乳腺癌 乳腺断层合成X线技术 合成2D图像 微钙化 

分 类 号：R318[医药卫生—生物医学工程] R445.4[医药卫生—基础医学]