CT测量主肺动脉/降主动脉截面积比值与COPD合并肺心病患者心功能的关系  

Correlation between CT-Measured MPA/DA Sectional Area and Cardiac Function in Patients with COPD and Pulmonary Heart Disease

作　　者：刘军[1] 何晓兰[2] 黄雨农[1] 蒋奕[1] LIU Jun;HE Xiao-lan;HUANG Yu-nong;JIANG Yi(Department of Radiology,the Sixth People's Hospital of Chengdu,Chengdu 610051,Sichuan Province,China;Department of Ultrasound Imaging,the Sixth People's Hospital of Chengdu,Chengdu 610051,Sichuan Province,China)

机构地区：[1]成都市第六人民医院放射科,四川成都610051 [2]成都市第六人民医院超声影像科,四川成都610051

出　　处：《中国CT和MRI杂志》2022年第2期66-68,共3页Chinese Journal of CT and MRI

基　　金：四川省卫生健康委员会科研课题(18PJ157)。

摘　　要：目的探讨CT测量主肺动脉(MPA)/降主动脉(DA)截面积比值与慢性阻塞性肺病(COPD)合并肺心病患者心功能的关系。方法选取2019年11月至2020年2月本院收治的103例COPD合并肺心病患者为病例组,另选取同期行健康体检人员50例为对照组。CT测量两组MPA和DA截面积,检测右心功能指标及实验室指标,Pearson检验MPA/DA截面积比值与心功能指标之间的相关性。结果病例组的MPA截面积、DA截面积、MPA/DA截面积比值、高敏C反应蛋白(hs-CRP)及脑利钠肽(BNP)分别为(808.64±98.64)mm^(2)、(498.34±94.57)mm^(2)、(1.62±0.12)、(96.34±20.47)mg/L、(69.56±6.38)ng/L,显著高于对照组的(592.06±23.52)mm^(2)、(449.53±89.36)mm^(2)、(1.31±0.18)、(4.37±1.49)mg/L、(20.93±3.15)ng/L。病例组的右室射血分数(EFRV)、右室舒张末期内径(EDRV)及右室前壁(RVAW)分别为(47.68±3.13)%、(11.07±1.19)mm、(3.41±0.51)mm,明显低于对照组的(63.31±5.46)%、(17.57±2.29)mm、(5.82±0.41)mm,差异均有统计学意义(P均<0.05)。MPA/DA截面积比值与hs-CRP及BNP呈正相关关系(r=0.6538/0.7106,P均<0.05),与EFRV、EDRV、RVAW呈负相关关系(r=-0.6964/-0.7839/-0.7322,P均<0.05)。结论CT测量MPA/DA截面积比值与COPD合并肺心病患者心功能密切相关,有助于监测病情。Objective To explore relationship between CT-measured main pulmonary artery(MPA)/descending aorta(DA)sectional area and cardiac function in patients with chronic obstructive pulmonary disease(COPD)and pulmonary heart disease(PHD).Methods A total of 103 patients with COPD and PHD who were admitted to the hospital from November 2019 to February 2020 were enrolled as case group.Fifty healthy people who underwent physical examination during the same period were enrolled as control group.CT was applied to measure sectional areas of MPA and DA in both groups.The right cardiac function indexes and laboratory indexes were detected.Pearson was applied to detect correlation between MPA/DA sectional area and cardiac function indexes.Results The sectional areas of MPA and DA,MPA/DA sectional area,high-sensitivity C-reactive protein(hs-CRP)and brain natriuretic peptide(BNP)in case group were(808.64±98.64)mm^(2),(498.34±94.57)mm^(2),(1.62±0.12),(96.34±20.47)mg/L and(69.56±6.38)ng/L,which were significantly higher than those in control group[(592.06±23.52)mm^(2),(449.53±89.36)mm^(2),(1.31±0.18),(4.37±1.49)mg/L,(20.93±3.15)ng/L].The right ventricular ejection fraction(EFRV),right ventricular end-diastolic diameter(EDRV)and right ventricular anterior wall(RVAW)in case group were(47.68±3.13)%,(11.07±1.19)mm and(3.41±0.51)mm,which are significantly lower than those in control group[(63.31±5.46)%,(17.57±2.29)mm,(5.82±0.41)mm,(P<0.05)].MPA/DA sectional area was positively correlated with hs-CRP and BNP(r=0.6538/0.7106,P<0.05),while negatively correlated with EFRV,EDRV and RVAW(r=-0.6964/-0.7839/-0.7322,P<0.05).Conclusion CT-measured MPA/DA sectional area is closely related to cardiac function in patients with COPD and PHD,which is conducive to monitoring conditions.

关 键 词：慢性阻塞性肺疾病 心功能 CT 

分 类 号：R445.3[医药卫生—影像医学与核医学] R563[医药卫生—诊断学]