^(18)F-FDG PET/CT与增强CT、MRI在诊断鉴别胰腺囊性良恶性病变的临床价值比较  

Comparison on Clinical Value of ^(18)F-FDG PET/CT,Enhanced CT,and MRI in Differential Diagnosis of Benign and Malignant Pancreas Cystic Lesions

作　　者：徐杰 陈艳林[2] 王雪伟[3] XU Jie;CHEN Yan-lin;WANG Xue-wei(Interventional Operation Room,Zhengzhou Central Hospital Affiliated to Zhengzhou University,Zhengzhou 450000,Henan Provicne,China;Department of Nuclear Medicine,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450000,Henan Provicne,China;Department of Radiology,Zhengzhou Sixth People's Hospital,Zhengzhou 450000,Henan Provicne,China)

机构地区：[1]郑州大学附属郑州中心医院介入手术室,河南郑州450000 [2]郑州大学第一附属医院核医学科,河南郑州450000 [3]郑州市第六人民医院放射科,河南郑州450000

出　　处：《中国CT和MRI杂志》2022年第2期99-101,共3页Chinese Journal of CT and MRI

基　　金：河南省卫生厅医学科技攻关项目(201903215)。

摘　　要：目的探究^(18)F-FDG PET/CT、增强CT及磁共振成像(MRI)三种诊断方法对胰腺囊性病变良、恶性的诊断价值。方法选择2017年1月至2019年1月我院收治的89例胰腺囊性病变患者作为研究对象,所有患者均行^(18)F-FDG PET/CT检查,52例行增强CT检查,48例行MRI检查。以病理诊断结果或12个月以上的随访结果作为“金标准”,分析各诊断方法的诊断价值。结果胰腺恶性病变及良性病变患者SUV_(max)平均值分别为7.15±4.28、2.41±0.71,差异具统计学意义(P<0.05);^(18)F-FDG PET/CT对胰腺良、恶性病变的诊断灵敏度、特异度、准确度、阳性预测值、阴性预测值分别为94.87%、98.00%、96.63%、97.37%、96.08%,各诊断效能值均明显高于增强CT及MRI诊断(P<0.05)。结论与增强CT及MRI比较,^(18)F-FDG PET/CT在鉴别胰腺囊性良、恶性病变方面具有一定优势,具有较好的临床应用价值。Objective To investigate diagnostic value of ^(18)F-FDG PET/CT,enhanced CT and magnetic resonance imaging(MRI)for benign and malignant pancreas cystic lesions.Methods 89 patients with pancreas cystic lesions who were admitted to the hospital from January 2017 to January 2019 were enrolled.All patients underwent ^(18)F-FDG PET/CT.52 cases underwent enhanced CT and 48 cases underwent MRI.Taking pathological diagnosis results or follow-up results for 12 months or longer as"golden standard",diagnostic value of each diagnostic method was analyzed.Results The mean values of SUVmax in patients with malignant pancreas lesions and benign lesions were(7.15±4.28),and(2.41±0.71),respectively(P<0.05).The sensitivity,specificity,accuracy,positive predictive value and negative predictive value of ^(18)F-FDG PET/CT for diagnosis of benign and malignant pancreas lesions were 94.87%,98.00%,96.63%,97.37%,and 96.08%,respectively.All diagnostic diagnostic efficiency values were significantly higher than those of enhanced CT and MRI(P<0.05).Conclusion Compared with enhanced CT and MRI,there are certain advantages of ^(18)F-FDG PET/CT in identifying benign and malignant pancreas cystic lesions,which is of good clinical application value.

关 键 词：胰腺 囊性病变 氟代脱氧葡萄糖 电子计算机断层扫描 磁共振成像 

分 类 号：R657.5[医药卫生—外科学] R445[医药卫生—临床医学]