用咪达唑仑与地西泮对惊厥持续状态患儿进行治疗的效果对比  

Effect comparison of midazolam and diazepam in the treatment of children with convulsive status

作　　者：杨娟 YANG Juan(Cao County People’s Hospital,Heze Shandong,274400)

机构地区：[1]曹县人民医院,山东菏泽274400

出　　处：《当代医药论丛》2022年第2期128-131,共4页

摘　　要：目的:比较使用咪达唑仑与地西泮对惊厥持续状态患儿进行治疗的效果。方法:选取2020年3月至2021年3月期间曹县人民医院收治的50例惊厥持续状态患儿作为研究对象。随机将这些患儿分为对照组(n=25)和观察组(n=25)。为对照组患儿使用地西泮进行治疗,为观察组患儿使用咪达唑仑进行治疗。然后观察两组患儿治疗开始至药物起效的时间、治疗开始至惊厥控制的时间、治疗的效果及发生不良反应的情况。结果:治疗后,观察组患儿治疗开始至药物起效的时间及治疗开始至惊厥控制的时间均短于对照组患儿,其治疗的总有效率高于对照组患儿,其不良反应的发生率低于对照组患儿,P<0.05。结论:与使用地西泮相比,使用咪达唑仑对惊厥持续状态患儿进行治疗起效的速度更快,效果更好,安全性更高。Objective:To compare the efficacy of midazolam and diazepam in the treatment of children with convulsive status.Methods:A total of 50 children with convulsive status admitted to Cao County People’s Hospital from March 2020 to March 2021 were selected as the study subjects.These children were randomly divided into control group(n=25)and observation group(n=25).The control group was treated with diazepam,and the observation group was treated with midazolam.Then,the time from the beginning of treatment to the effect of drugs,the time from the beginning of treatment to the control of convulsion,the effect of treatment and the occurrence of adverse reactions were observed in the two groups.Results:After treatment,the time from the beginning of treatment to drug effect and the time from the beginning of treatment to convulsion control in the observation group were shorter than those in the control group,the total effective rate of treatment was higher than that in the control group,and the incidence of adverse reactions was lower than that in the control group,P<0.05.Conclusions:Compared with diazepam,midazolam is quicker,more effective,and safer in the treatmen t of children with convulsive status.

关 键 词：小儿 惊厥持续状态 咪达唑仑 地西泮 

分 类 号：R720.597[医药卫生—急诊医学]