纤支镜肺泡灌洗在脑死亡边缘性供肺维护中的作用  

The Effect of Bronchoscopic Alveolar Lavage on the Maintenance of Borderline Donor Lung in Brain Death

作　　者：龚丽明[1] 李立[2] 冉江华[2] 李兰[3] 张升宁[2] 李超[4] 王胤佳[4] 王东坤 郑莉 张国峰[1] GONG Lingming;LI Li;RAN Jianghua;LI Lan;ZHANG Shengning;LI Chao;WANG Yinjia;WANG Dongkun;ZHENG Li;ZHANG Guofeng(Dept.of Cardiothoracic Surgery,The 1st People’s Hospital of Kunming,Kunming Yunnan 650011;Dept.of Hepatological Surgery,The 1st People’s Hospital of Kunming,Kunming Yunnan 650011;Dept.of Ophthalmology,The 1st People’s Hospital of Kunming,Kunming Yunnan 650011;Dept.of Intensive Care Unit,The 1st People’s Hospital of Kunming,Kunming Yunnan 650011;Dept.of Thoracic Surgery,The 1st People’s Hospital of Qujing,Qujing Yunnan 655000,China)

机构地区：[1]昆明市第一人民医院心胸外科,云南昆明650011 [2]昆明市第一人民医院肝胆外科,云南昆明650011 [3]昆明市第一人民医院眼科,云南昆明650011 [4]昆明市第一人民医院重症监护室,云南昆明650011 [5]曲靖市第一人民医院胸外科,云南曲靖655000

出　　处：《昆明医科大学学报》2022年第1期89-95,共7页Journal of Kunming Medical University

基　　金：昆明市卫生科技人才培养项目暨“十百千”工程基金资助项目[2016-sw(省)-40];昆明市科技局科技保障民生发展重点基金资助项目(2019-1-S-25318000001168)。

摘　　要：目的研究纤支镜肺泡灌洗在脑死亡边缘性供肺维护中的作用。方法选取昆明医科大学附属甘美医院2017年9月至2019年12月收治的符合纳入标准的脑死亡患者,按照随机分组原则,在常规维护的基础上,分为纤支镜肺泡灌洗组(实验组)及对照组,通过2组胸片、动脉血气(氧合指数)、纤支镜检查等指标的比较,进行统计学分析。结果2组实验后氧合指数、胸片、纤支镜镜下表现评分均低于实验前评分,差异具有统计学意义(P<0.05),且2组试验后有效率比较差异有统计学意义(P<0.05),实验组有效率大于对照组。结论纤支镜肺泡灌洗可以作为一种有效维护供肺的技术,是提高边缘性供肺利用的有效手段。Objective To investigate the effect of bronchoscopic alveolar lavage on the maintenance of borderline donor lung in brain death.Methods The brain death patients meeting the inclusion criteria and admitted to Ganmei Hospital of Kunming Medical University from September 2017 to December 2019 were randomly divided into the fiberoptic bronchoscopy alveolar lavage group(experimental group)and the control group on the basis of routine maintenance.Statistical analysis was carried out through the comparison of chest film,arterial blood gas(oxygenation index),fiberoptic bronchoscopy and other indexes between the two groups.Result The scores of oxygenation index,chest radiograph and fiberbronchoscope performance of the two groups after the experiment were all lower than those before the experiment the differences were statistically significant(P<0.05),and there was statistically significant difference in effective rate between the two groups(P<0.05).The effective rate of the experimental group was higher than that of the control group.Conclusion Fiberbronchoscope alveolar lavage can be used as an effective technique to maintain the donor lung and has a wide application prospect.

关 键 词：肺移植 脑死亡 边缘性供肺 纤支镜肺泡灌洗 供肺维护 

分 类 号：R617[医药卫生—外科学] R653[医药卫生—临床医学]