和解法治疗小儿反复呼吸道感染  

A study on the clinical effect of the reconciliation method in the treatment of infantile recurrent respiratory tract infection

作　　者：彭楠 周静冬[1] 虞坚尔[1] 廖芳菊 吕琦 朱迪[1] 冯晓纯[3] PENG Nan;ZHOU Jingdong;YU Jian’er;LIAO Fangju;LV Qi;ZHU Di;FENG Xiaochun(Shanghai Municipal Hospital of Traditional Chinese Medicine Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 200070,China;Putuo Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 200062,China;Affiliated Hospital of Changchun University of Chinese Medicine,Changchun 130021,China)

机构地区：[1]上海中医药大学附属市中医医院,上海200070 [2]上海中医药大学附属普陀医院,上海200062 [3]长春中医药大学附属医院,长春130021

出　　处：《吉林中医药》2021年第12期1627-1630,共4页Jilin Journal of Chinese Medicine

基　　金：上海市科学技术委员会(16411951000);国家中医药管理局第四批全国中医(临床、基础)优秀人才研修项目(国中医药人教发〔2017〕24号);国家中医药管理局(2019XZZX-EK002)。

摘　　要：目的评价和解法治疗小儿反复呼吸道感染优化方案的有效性和安全性。方法采用随机、对照、优效试验设计。治疗组选用和解2方颗粒剂(柴胡16 g,黄芩6 g,太子参6 g,菟丝子9 g,姜半夏6 g,生黄芪9 g,防风6 g,白术9 g,炙甘草6 g),对照组选用泛福舒。结果治疗组228例,临床痊愈率为86.8%;对照组229例,临床痊愈率为62.9%。2组疗效比较,治疗组痊愈率高于对照组(P<0.01)。用药1年后,上呼吸道感染、支气管炎发作次数,支气管炎、肺炎的发热时间的组间比较,中医证候积分比较差异均具有统计学意义(P<0.05),治疗组均优于对照组。结论和解法治疗小儿反复呼吸道感染缓解期疗效优于泛福舒,尤其在缩短发热时间、改善中医证候积分等方面更具优势。Objective To evaluate the effectiveness and safety of the reconciliation method in the optimized treatment regimen of infantile recurrent respiratory tract infection.Methods A randomized,controlled,and superior-efficiency test design was adopted in the study.The treatment group was given the Hejie Prescription Granules 2(Chinese thorowax root for 16 g,baical skullcap root for 6 g,heterophylly falsestarwort root for 6 g,dodder seeds for 9 g,ginger processed pinellia for 6 g,unprocessed milkvetch root for 9 g,divaricate saposhnikovia root for 6 g,largehead atractylodes rhizome for 9 g,processed liquorice root for 6 g),while the control group was treated with broncho-vaxom.Results The clinical recovery rate of the treatment group(86.8%in 228 cases)was higher than that of the control group(62.9%in 229 cases)(P<0.01).After one year of treatment,the treatment group was significantly better than the control group in the incidence number of upper respiratory tract infection and bronchitis,in the fever time of bronchitis and pneumonia and in the TCM syndrome scores(P<0.05).Conclusion The reconciliation method is more effective than broncho-vaxom in the treatment of infantile recurrent respiratory tract infection in the remitting stage,especially in shortening the fever time and improving TCM syndrome scores.

关 键 词：和解2方 小儿 呼吸道感染 缓解期 和解法 

分 类 号：R725.6[医药卫生—儿科]