冰糖草二萜类成分的研究进展  

Progress of Research on Diterpenoids from Scoparia dulcis L.

作　　者：孙万莹 董琳[1] 李祎莹 韩丽芳 陈丽珍[1] 王瑞琪 张璐 张勇[2] 张小坡[1] SUN Wanying;DONG Lin;LI Yiying;HAN Lifang;CHEN Lizhen;WANG Ruiqi;ZHANG Lu;ZHANG Yong;ZHANG Xiaopo(School of Pharmacy,Hainan Medical University,Haikou 571199,China;School of Basic Medicine and Life Sciences,Hainan Medical University,Haikou 571199,China)

机构地区：[1]海南医学院药学院,海南海口571199 [2]海南医学院基础医学与生命科学院,海南海口571199

出　　处：《药学进展》2021年第11期862-867,共6页Progress in Pharmaceutical Sciences

基　　金：国家自然科学基金(No.82060778)。

摘　　要：冰糖草在世界各地作为传统药物被广泛使用。冰糖草中的二萜类成分结构独特,Labdane和Scopadulane型二萜为其主要成分,具有抗糖尿病、抗病毒、抗疟疾等多种生物活性。对冰糖草中的二萜类化合物的发现、合成和药理作用进行综述,旨在为其进一步开发利用提供参考。Scoparia dulcis L. is an important traditional medicine used worldwide to treat many diseases. Previous investigation on chemical constituents of Scoparia dulcis L. revealed that the diterpenoids in the plant are unique in structure, with Labdane and Scopadulane diterpenoids being the main components, which have a variety of biological activities such as anti-diabetes, anti-virus and anti-malaria..The discovery, synthesis and pharmacological activities of diterpenoids in Scoparia dulcis L. were reviewed in this article, so as to provide reference for further utilization of Scoparia dulcis L.

关 键 词：冰糖草 二萜 合成 药理活性 

分 类 号：R284[医药卫生—中药学]