新疆210例骨关节炎临床特点及危险因素分析  

Analysis about clinical characteristics and risk factors of 210 Patients with osteoarthritis in Xinjiang

作　　者：刘勇 吴雪 罗采南[2] 钟岩[2] 库尔班江·依麦提[2] 米克拉依·曼苏尔[2] 孟新艳[2] 武丽君[2] LIU Yong;WU xue;LUO Cai Nan;ZHONG Yan;Kuerbanjiangr Yimaiti;Mikelayi Mansuer;Meng Xin-yan;WU Li-jun(Aksu Uygur medical hospital,Xinjiang,Aksu,843000,China;People’s Hospital of Xinjiang Uygur Autonomous Region,Urumqi,830001,China)

机构地区：[1]阿克苏地区维吾尔医医院,新疆阿克苏843000 [2]新疆维吾尔自治区人民医院,乌鲁木齐830001

出　　处：《新疆医学》2021年第11期1236-1238,共3页Xinjiang Medical Journal

基　　金：阿克苏地区人才项目(项目编号:201916)。

摘　　要：目的研究目的是调查中国新疆地区临床膝关节骨关节炎(Knee osteoarthritis,KOA)的流行病学特征和危险因素。方法回顾性纳入2020年1月至2021年5月就诊于新疆维吾尔自治区人民医院风湿免疫科及阿克苏地区维吾尔医医院风湿科并明确诊断KOA的患者。收集患者基本信息,主要包括:年龄、性别、职业、吸烟、饮酒、体质指数(BMI)等信息,KOA的诊断标准采用美国风湿病协会1995年修订的诊断标准,数据使用SPSS26统计软件进行分析。结果本研究共纳入210例KOA患者,平均年龄57.2±10.1,男性53名(占总体25.2%),女性157名(占总体74.8%)。KOA患者年龄、BMI明显高于对照组,组间对比存在显著差异(P<0.05)。女性、农民、教育程度低的人群更易患KOA。采用多因素回归分析显示,年龄(OR=1.037,95%CI:1.018-1.057)、女性(OR=1.865,95%CI:1.176-2.959)、BMI(OR=1.108,95%CI:1.048-1.172)为KOA相关的危险因素,而教育水平与农民与KOA患病无明显相关性。结论新疆KOA患病率随年龄呈递增趋势,女性患病率高于男性,其中年龄、女性、肥胖可能与KOA的发病有关。Objective To investigate the epidemiological characteristics and risk factors of clinical knee osteoarthritis(KOA)in Xinjiang.Methods Patients who were admitted to the department of Rheumatology and Immunology at People’s hospital of Xinjiang Uygur Autonomous Region and were diagnosed with KOA from January 2020 to May 2021 were retrospectively included.The basic information of patients was collectedincluding age,gender,occupation,smoking,alcohol consumption,body mass index(BMI),etc.The diagnostic criteria for KOA adopted the diagnostic criteria revised by the American Association of Rheumatology in 1995,and the data were analyzed using SPSS 26 statistical software.Results A total of 210 patients with KOA were included in this study,with a mean age of 57.2±10.1 years old.There were 53 males(25.2%)and 157 females(74.8%).The age and BMI of the patients with KOA were significantly higher than those of control group,and there were significant differences between two groups(P<0.05).Female,farmers,and people with less education are more likely to suffer from KOA.Multivariate regression analysis showed that age(OR was 1.037;95%CI was 1.018-1.057),female(OR was 1.865;95%CI was 1.176-2.959),BMI(OR was 1.108,95%CI was 1.048-1.172)were the risk factors associated with KOA,while there was no significant correlation between education level,farmer and KOA incidence.Conclusions The prevalence of KOA in Xinjiang is increasing with age,and the prevalence of KOA in females is higher than that in males.Age,females and obesity may be related to the incidence of KOA.

关 键 词：骨关节炎 流行病学特征 危险因素 

分 类 号：R593.2[医药卫生—内科学]