新疆地区10年主动脉夹层临床资料研究及生存分析  

Clinical data study and survival analysis of aortic dissection in Xinjiang for 10 years

作　　者：李晖[1] 韩素霞 毕晓娟[3] LI Hui;HAN Suxia;BI Xiaojuan(The First Affiliated Hospital of Xinjiang Medical University,Urumqi 830054,China;Shanghai Pudong New Area People’s Hospital,Shanghai 201200,China;Clinical Research Institute of Xinjiang Medical University,Urumqi 830054,China)

机构地区：[1]新疆医科大学第一附属医院,乌鲁木齐830054 [2]上海浦东新区人民医院,上海201200 [3]新疆医科大学临床研究院,乌鲁木齐830054

出　　处：《新疆医学》2021年第11期1289-1293,共5页Xinjiang Medical Journal

基　　金：新疆维吾尔自治区自然科学基金项目(项目编号:2016D01C301)。

摘　　要：目的分析新疆医科大学第一附属医院10年间1212例主动脉夹层患者部分临床资料,初步探讨主动脉夹层发病规律。方法收集2008-01-01~2017-12-31在本院住院的1212例主动脉夹层患者数据进行分析,2008-01-01~2011-12-31为第一组,2012-01-01~2017-12-31为第二组。结果1212例AD患者中,1182例符合纳入标准;A型及B型主动脉夹层的年龄分布,差异无统计学意义,41-50岁组457例(38.7%),发病人数最多,Stanford A型患者469例,Stanford B型患者713例,A型与B型比例为1∶1.51;主动脉夹层发病有一定的季节性,1、2、3、4、12月的入院患者较多。在所有主动脉夹层患者中,合并高血压病患者446例(37%);新疆地区主动脉夹层患者的地区分布以乌鲁木齐市最多452例(38.2%),昌吉地区次之176例(14.9%)。应用kaplanmeier绘制生存曲线,第二组与第一组生存比较,差异有统计学意义(χ^(2)=21.943,P=0.000<0.001),不同治疗方式对主动脉夹层患者生存比较,差异有统计学意义(χ^(2)=318.324,P=0.000<0.001)。结论男性,年龄>40岁是主动脉夹层发病的危险因素之一。男性患者以Stanford B型为主,女性患者B型多于A型。主动脉夹层多在春冬季发病。Objective To analyze the epidemiological data of 1212 patients with aortic dissection in the past 10 years,and to preliminary study the occurrence regularity of aortic dissection in the first affiliated hospital of Xinjiang Medical University.Methods A total of 1212 cases of aortic dissection diagnosed at the First Affiliated Hospital of Xinjiang Medical University from January 1,2008 to December 31,2017 were analyzed retrospectively.2008-01-01~2011-12-31 was the first group,2012-01-01~2017-12-31 was the second group.Results 1182 Of 1212 AD patients met the inclusion criteria.There was no significant difference in age distribution between type A and type B aortic dissection.There were 457 cases(38.7%)in 41-50 years old group,there were 469 patients with Stanford type A and 713 patients with Stanford type B.the ratio of type A to type B was 1∶1.51.The incidence of aortic dissection was seasonal,and the patients admitted in January,February,March,April and December are more.Among all the patients with aortic dissection,446(37%)had hypertension.The regional distribution of aortic dissection patients in Xinjiang at most was Urumqi with 452 cases(38.2%),followed by Changji with 176 cases(14.9%).Using Kaplanmeier to draw survival curve,the second group and the first group survival were statistically significant(χ^(2)=21.943,P=0.000<0.001),different treatment methods on aortic dissection survival comparison were statistically significant(χ^(2)=318.324,P=0.000<0.001).Conclusions Male,aged>40 years,is one of the risk factors for aortic dissection.Stanford type B was the main type in male patients,and type B was more than type A in female patients.Aortic dissection usually occurs in spring and winter.

关 键 词：主动脉夹层 流行病学 生存分析 新疆 

分 类 号：R543.1[医药卫生—心血管疾病]