点阵CO_(2)激光治疗女性轻中度压力性尿失禁的临床疗效分析  

Clinical efficacy analysis of fractional CO_(2) laser in the treatment of female with mild-to-moderate stress urinary incontinence

作　　者：高振涛 周祥福[1] 陈雪莲[1] 丁燕珊 高静 马秋平 饶丹灵 刘柏隆[1] Gao Zhentao;Zhou Xiangfu;Chen Xuelian;Ding Yanshan;Gao Jing;Ma Qiuping;Rao Danling;Liu Bolong(Department of Urology,the Third Affliated Hospital of Sun Yat-sen University,Guangzhou 510630,China)

机构地区：[1]中山大学附属第三医院泌尿外科,广州510630

出　　处：《中华腔镜泌尿外科杂志（电子版）》2022年第1期40-44,共5页Chinese Journal of Endourology(Electronic Edition)

基　　金：国家自然科学基金(81800666);广东省自然科学基金(2016A030313192,2018A0303130330,2021A1515010354);广州市科技计划项目(202103000035)。

摘　　要：目的探究经阴道点阵CO_(2)激光治疗女性轻、中度压力性尿失禁(SUI)的临床疗效。方法回顾性研究本院2017年1月至2020年12月收治的轻中度SUI女性患者。激光治疗组41例,进行点阵CO_(2)激光联合盆底肌训练治疗,每月治疗1次,共治疗3次;生物反馈治疗组20例,采用生物反馈电刺激联合盆底肌训练。比较两组患者治疗后临床疗效、国际尿失禁委员会尿失禁问卷简表(ICI-Q-SF)、尿失禁生活质量问卷(I-QOL)及女性性功能量表(FSFI)评分。结果治疗后,激光治疗组总有效率为92.68%,疗效强于生物反馈组(P<0.05);治疗后ICI-Q-SF、I-QOL、FSFI评分均得到改善(P<0.01);与生物反馈治疗组比较,激光治疗组I-QOL、FSFI增加更显著(P<0.05),ICI-Q-SF评分明显降低(P<0.01)。3例患者治疗时述阴道烧灼感,休息后好转,5例患者出现一过性的尿急,部分患者阴道分泌物增多后自行恢复,整个治疗过程无其他不良事件发生。结论点阵CO_(2)激光治疗能够有效改善轻、中度SUI患者的临床症状,提高患者性功能和生活质量,具有良好临床疗效。Objective To explore the clinical efficacy of transvaginal fractional CO_(2) laser in the treatment of female with mild-to-moderate stress urinary incontinence(SUI).Methods A retrospective study of female patients with mild-to-moderate SUI admitted to our hospital from January 2017 to December 2020.41 cases received fractional CO_(2) laser treatment once a month for 3 times(Group A).Meanwhile,20 cases received biofeedback electrostimulation(Group B).Both groups were combined with pelvic floor muscle training.The clinical efficacy,International Consultation on Incontinence Questionnaire-short Form(ICI-Q-SF),Quality of Life Questionnaire(I-QOL)and Female Sexual Function Inventory(FSFI)scores were compared between the two groups after treatment.Results After treatment,the total effective rate of Group A was 92.68%,which was higher than that in Group B(P<0.05);the scores of ICI-Q-SF,I-QOL and FSFI improved after treatment(P<0.01)in Group A;Compared with Group B,the I-QOL and FSFI in Group A increased significantly(P<0.05),and the ICI-Q-SF score was significantly reduced(P<0.01).Three patients reported vaginal burning sensation during treatment,which relieved after rest,five patients showed transient urgency of urination,and some patients recovered spontaneously after increased vaginal secretion.No other adverse events occurred during the study.Conclusion The fractional CO_(2) laser was found to be effective for mild-to-moderate SUI,according to a variety of objective and subjective parameters,which can effectively improve the clinical symptoms,the sexual function and quality of life of patients.

关 键 词：压力性尿失禁 二氧化碳激光 电刺激 盆底肌训练 

分 类 号：R711.59[医药卫生—妇产科学]