糖尿病心肌病早期诊断标志物研究进展  

The Research Progress on Biomarkers for the Early Diagnosis of Diabetic Cardiomyopathy

作　　者：张婕鑫 刘华伟 汪汉 张彦懿 陈欣 ZHANG Jiexin;LIU Huawei;WANG Han;ZHANG Yanyi;CHEN Xin(The Third People’s Hospital of Chengdu/Affiliated Hospital of Southwest Jiaotong University, Chengdu 610031, China;General Hospital of Western Theater Command, Chengdu 610083, China)

机构地区：[1]成都市第三人民医院/西南交通大学附属医院,四川成都610031 [2]西部战区总医院,四川成都610083

出　　处：《标记免疫分析与临床》2021年第12期2166-2171,2176,共7页Labeled Immunoassays and Clinical Medicine

基　　金：西南交通大学基础研究培育支持计划基金(编号:YGJH2020-L)。

摘　　要：糖尿病心肌病是糖尿病患者的重要并发症,以心脏僵硬、心肌纤维化等为主要特征,最终进展为心力衰竭而死亡。糖尿病心肌病患者在疾病后期并发症不可逆转前往往没有症状,因此探索可以识别早期糖尿病心肌病的生物标志物,对于降低糖尿病心肌病患者的死亡率具有重要意义。本文旨在通过文献计量学方法对近30年来糖尿病心肌病诊断的研究进行综述,预测该领域在全球的发展趋势,为开发临床糖尿病心肌病早期诊断标志物提供重要思路。Diabetic cardiomyopathy,one of the severe complications of diabetes mellitus,characterized by myocardial stiffness and cardiac fibrosis,can eventually progress to heart failure and death.Patients with diabetic cardiomyopathy are often asymptomatic until the stage when advanced complications of the disease become irreversible.Thus,it is of great significance to explore biomarkers that can identify early diabetic cardiomyopathy to reduce the high incidence.This paper reviews the research on diagnostic markers of diabetic cardiomyopathy in recent 30 years by bibliometrics,predicts the future development trend of this field world-wide,and provides new insights for the clinical markers of the early diagnosis of diabetic cardiomyopathy.

关 键 词：糖尿病心肌病 诊断 标志物 文献计量学 

分 类 号：R587.2[医药卫生—内分泌]