激光扫描共聚焦显微技术在高分子科学研究中的应用  

Application of Laser Scanning Confocal Microscopy in the Study of Polymer Science

作　　者：张滢滢 郭毅 沈烈[1] ZHANG Ying-ying;GUO Yi;SHEN Lie(MOE Key Laboratory of Macromolecular Synthesis and Functionalization,Department of Polymer Science and Engineering,Zhejiang University,Hangzhou 310027,China)

机构地区：[1]高分子合成与功能构造教育部重点实验室,浙江大学高分子科学与工程学系,杭州310027

出　　处：《高分子通报》2022年第1期78-85,共8页Polymer Bulletin

摘　　要：激光扫描共聚焦显微技术作为一种深层形态结构分析的重要研究方法,避免了繁琐的实验操作以及对样品的破坏,可直接给出材料内部结构的三维图像,在生物学、医学、材料科学和冶金学等研究领域都有广泛的应用。本文阐述了激光扫描共聚焦显微镜的工作原理及技术优势,综述了激光扫描共聚焦显微技术在高分子科学研究领域的应用进展,包括聚合物多组分体系、聚合物颗粒、聚合物膜、嵌段共聚物自组装以及药物控释表征,以期为更多科研人员提供有益参考。Laser scanning confocal microscopy is an important research method for the analysis of internal structure of materials without complex experimental operation and prior sample destruction.It can give a three-dimensional image of the internal structure directly and is widely used in the research of biology,medicine,materials science and metallurgy,etc.This paper introduced the working principle and advantages of laser scanning confocal microscope.Moreover,the application progress in the field of polymer science was summarized,which includes polymer multi-component systems,polymer particles,polymer films,self-assembly of block copolymers,and controlled release of drugs,in order to provide useful reference for more scientific researchers.

关 键 词：激光扫描共聚焦显微镜 高分子科学 应用 

分 类 号：TQ317[化学工程—高聚物工业]