黑龙江省某医院抽样人群血清25羟维生素D水平回顾性研究  

A retrospective study on serum 25(OH)D level of the sampled population in a hospital in Heilongjiang province

作　　者：孟佳[1] 许亚茹 缪晓涵 孟霖[2] 张明明[1] 姜礼红[1] MENG Jia;XU Yagu;MIAO Xiaohan;MENG Lin;ZHANG Mingming;JIANG Lihong(Department of General Medical,the Second Affiliated Hospital of Harbin Medical University,Harbin 150086;Cadre Ward,the Affiliated Hospital of Jilin Medical University,Changchun 130012,China)

机构地区：[1]哈尔滨医科大学附属第二医院全科医疗科,黑龙江哈尔滨150086 [2]吉林大学第一医院干部病房,吉林长春130012

出　　处：《中国骨质疏松杂志》2022年第1期62-65,69,共5页Chinese Journal of Osteoporosis

摘　　要：目的回顾性分析黑龙江省某医院2017年10月至2018年10月住院患者的维生素D[25(OH)D]水平,并探讨其影响因素。方法收集该医院病案系统2017-2018年所有测定25(OH)D的病例,获取病例信息,将25(OH)D水平按照不同信息分类并比较。结果研究样本包括876名研究对象,25(OH)D缺乏组与不足组共799人,占总人数的91.21%,25(OH)D充足组77人,占8.79%。男性组25(OH)D水平高于女性组,差异具有统计学意义(P<0.001)。男性组中年龄与25(OH)D水平的相关性差异无统计学意义(P=0.772),女性组呈弱正相关(P<0.05)。骨质疏松组(OP)与非骨质疏松组(NOP)间25(OH)D水平差异无统计学意义(P=0.714),女性骨质疏松治疗组25(OH)D水平高于非骨质疏松组(P=0.024)。结论本研究中样本总体25(OH)D水平偏低,提示该地区人群25(OH)D水平普遍偏低。25(OH)D水平与性别、生活方式有关,与年龄、是否患有骨质疏松无关,服用活性维生素D不能提升血清25(OH)D水平。黑龙江地区人群应当注意补充25(OH)D,可以通过改善生活方式或口服维生素D的方式补充。Objective To retrospectively analyze the levels of vitamin D(25(OH)D)of hospitalized patients in a hospital in Heilongjiang province from October 2017 to October 2018,and to discuss the influential factors.Methods Data were collected from the cases whose 25(OH)D was determined in the hospital during 2017-2018.The case information was retrieved.The 25(OH)D levels were classified and compared according to different information.Results The study sample included 876 subjects,including 799 subjects in the 25(OH)D deficiency group and the insufficient group,accounting for 91.21%of the total population,and 77 subjects in the 25(OH)D sufficient group,accounting for 8.79%.The level of 25(OH)D in the male group was higher than that in the female group,and the difference was statistically significant(P<0.001).There was no statistically significant correlation between age and 25(OH)D level in the male group(P=0.772),but there was a weak positive correlation in the female group(P<0.05).There was no significant difference in 25(OH)D level between the osteoporosis group(OP)and the non-osteoporosis group(NOP,P=0.714),but the level of 25(OH)D in the osteoporosis treatment group was higher than that in the NOP group(P=0.024).Conclusion In this study,the 25(OH)D level of the whole sample is low,suggesting that the 25(OH)D level of the population in this area is generally low.The level of 25(OH)D is associated with gender and lifestyle,but is not associated with age or osteoporosis.Taking active vitamin D does not improve the level of 25(OH)D.People in Heilongjiang should pay attention to 25(OH)D supplementation,which can be achieved through lifestyle improvement or oral vitamin D supplementation.

关 键 词：维生素D 25羟维生素D 回顾性研究 黑龙江 

分 类 号：R681[医药卫生—骨科学]