桑白皮汤加减联合常规西药治疗老年慢性阻塞性肺疾病临床研究  

Clinical Study on Modified Sangbaipi Tang Combined with Routine Western Medicine for Senile Patients with Chronic Obstructive Pulmonary Disease

作　　者：倪佳伟 沈爱娟[2] NI Jiawei;SHEN Aijuan

机构地区：[1]嘉善县中医医院内一科,浙江嘉善314100 [2]嘉兴市中医医院肺病科,浙江嘉兴314000

出　　处：《新中医》2021年第23期100-103,共4页New Chinese Medicine

摘　　要：目的:观察桑白皮汤加减联合常规西药治疗老年慢性阻塞性肺疾病(慢阻肺)的临床疗效。方法:回顾性选取老年慢阻肺患者200例作为研究对象,根据治疗方式不同分成观察组和对照组各100例。对照组给予常规西医对症治疗,观察组在对照组基础上予以桑白皮汤加减治疗。比较2组临床疗效、圣乔治呼吸问卷(SGRQ)评分、炎性指标水平。结果:观察组总有效率为100%,高于对照组96.0%,差异有统计学意义(P<0.05)。治疗前,2组呼吸症状、活动能力、疾病影响、总评分比较,差异无统计学意义(P>0.05)。治疗后,2组呼吸症状、活动能力、疾病影响、总评分低于治疗前,且观察组各项评分均低于对照组,差异有统计学意义(P<0.05)。治疗前,2组C-反应蛋白(CRP)、降钙素原(PCT)、红细胞沉积率(ESR)水平比较,差异无统计学意义(P>0.05)。治疗后,2组CRP、PCT、ESR水平低于治疗前,且观察组CRP、PCT、ESR水平均低于对照组,差异有统计学意义(P<0.05)。结论:桑白皮汤加减联合常规西药治疗老年慢阻肺患者的疗效满意,能够降低炎性因子水平,改善呼吸症状。Objective:To observe the clinical effect of modified Sangbaipi tang combined with routine western medicine for senile patients with chronic obstructive pulmonary disease(COPD).Methods:A total of 200 cases of senile patients with COPD were retrospectively selected as research objects,and divided into the observation group and the control group according to different treatment methods,with 100 cases in each group.The control group was given routine western medicine symptomatic treatment,and the observation group was additionally treated with modified Sangbaipi tang based on the treatment of the control group.The clinical effects,St.George's Respiratory Questionnaire(SGRQ)scores and inflammatory indexes were compared between the two groups.Results:The total effective rate was 100%in the observation group,higher than that of 96.0%in the control group,the difference being significant(P<0.05).Before treatment,there was no significant difference being found in the comparison of respiratory symptoms,activity,disease impact and the total scores between the two groups(P>0.05).After treatment,respiratory symptoms,activity,disease impact and the total scores in the two groups were lower than those before treatment,and the above scores in the observation group were lower than those in the control group,the difference being significant(P<0.05).Before treatment,there was no significant difference being found in the comparison of the levels of C-reactive protein(CRP),procalcitonin(PCT)and erythrocyte sedimentation rate(ESR)between the two groups(P>0.05).After treatment,the levels of CRP,PCT and ESR in the two groups were lower than those before treatment,and the above levels in the observation group were lower than those in the control group,the difference being significant(P<0.05).Conclusion:The therapy of modified Sangbaipi tang combined with routine western medicine has a satisfactory curative effect in treating senile patients with COPD,which can reduce the levels of inflammatory factors and improve respiratory symptoms.

关 键 词：慢性阻塞性肺疾病 桑白皮汤 圣乔治呼吸问卷 C-反应蛋白 降钙素原 红细胞沉积率 

分 类 号：R563[医药卫生—呼吸系统]