心脑联合CT血管成像对急性脑梗死头颈动脉与冠状动脉粥样硬化的相关性研究  

Correlation of atherosclerosis between coronary and cervicocephalic artery in patients with acute cerebral infarction with combined coronary,carotid and cerebral CT angiography

作　　者：郑冲 曹丽珍[1,2] 傅璠 赵澄 郭道德[1,2] 王志超 卢洁[1,2] ZHENG Chong;CAO Lizhen;FU Fan;ZHAO Cheng;GUO Daode;WANG Zhichao;LU Jie(Department of Radiology and Nuclear Medicine,Xuanwu Hospital,Capital Medical University,Beijing 100053,China;Beijing Key Laboratory of Magnetic Resonance Imaging and Brain Informatics,Beijing 100053,China)

机构地区：[1]首都医科大学宣武医院放射与核医学科,北京100053 [2]磁共振成像脑信息学北京市重点实验室,北京100053

出　　处：《实用放射学杂志》2021年第12期1931-1935,共5页Journal of Practical Radiology

基　　金：北京市自然科学基金项目(Z190014);北京市医院管理局“登峰”计划专项经费资助项目(DFL20180802)。

摘　　要：目的探讨一站式心脑联合CT血管成像(CTA)对急性脑梗死患者头颈部斑点状钙化(SC)与冠状动脉钙化积分(CACS)的相关性。方法本研究共纳入45例患者,包括经头颅MRI或CT平扫证实的首次发生急性脑梗死患者25例(急性脑梗死组),以及经颈动脉超声证实亚临床颈动脉粥样硬化患者20例(动脉粥样硬化组)。患者均在首次影像学检查后1周内行一站式心脑联合CTA检查。分别以SC及CACS评估头颈部及冠状动脉粥样硬化,比较2组患者SC数量及CACS的差异,并行SC与CACS的相关性分析。结果急性脑梗死组患者SC及CACS均明显高于动脉粥样硬化组(SC总数:5.76±12.2 vs 1.30±1.89,P<0.001;CACS:307.68±372.99 vs 68.00±110.03,P=0.037)。急性脑梗死组与动脉粥样硬化组患者的SC与CACS均呈显著正相关(r=0.814,P<0.001;r=0.688,P=0.001)。结论急性脑梗死患者SC与CACS呈显著正相关,对急性脑梗死患者心脑血管联合评估具有重要意义。Objective To investigate the association between spotty calcium(SC)in cervicocephalic artery and coronary artery calcium score(CACS)in patients with acute cerebral infarction by using one-stop cervicocephalic and coronary CT angiography(CTA).Methods A total of 45 patients were enrolled in this study,including 25 patients with acute cerebral infarction(acute cerebral infarction group)confirmed by brain MRI or nonenhanced CT,and 20 patients with subclinical carotid atherosclerosis confirmed by carotid ultrasonography(atherosclerosis group).Each subject underwent one-stop cervicocephalic and coronary CTA within one week after the initial imaging examination.SC and CACS were used to evaluate the cervicocephalic and coronary atherosclerosis,respectively.The number of SC and the difference in CACS between the two groups were compared,and the correlation between SC and CACS was analyzed.Results The SC and CACS in the acute cerebral infarction group were both significantly higher than those in the atherosclerosis group(total SC count:5.76±12.2vs1.30±1.89,P<C0.001;CACS:307.68±372.99 vs 68.00±110.03,P=0.037).Therewasasignificant positive correlation between SC and CACS in the acute cerebral infarction group and atherosclerosis group(r=0.814,P<0.001;r=0.688,P=0.001,respectively).Conclusion There was significant association between SC and CACS in acute cerebral infarction patients,which suggests combined assessment of cerebrovascular and cardiovascular would be of importance for those patients.

关 键 词：计算机体层成像 血管造影术 钙化积分 动脉粥样硬化 

分 类 号：R814.42[医药卫生—影像医学与核医学] R814.43[医药卫生—放射医学]