A smartphone-based calibration-free portable urinalysis device  

基于智能手机的免校准便携式尿液分析设备

作　　者：GUO Dong LI Gen MIAO Jia-qi SHEN Ya-jing 郭栋;李根;苗佳麒;申亚京(Shenzhen Research Institute of City University of Hong Kong,Shenzhen 518000,China;Department of Biomedical Engineering,City University of Hong Kong,Hong Kong SAR 999077,China)

机构地区：[1]Shenzhen Research Institute of City University of Hong Kong,Shenzhen 518000,China [2]Department of Biomedical Engineering,City University of Hong Kong,Hong Kong SAR 999077,China

出　　处：《Journal of Central South University》2021年第12期3829-3837,共9页中南大学学报（英文版）

基　　金：Projects(61922093,U1813211) supported by the National Natural Science Foundation of China;Projects(SGDX20201103093003017,JCYJ20200109114827177) supported by Shenzhen Key Basic Research Project,China。

摘　　要：As one of the most common medical diagnosis methods, urinalysis is a highly demanded technique for screening tests or daily monitoring of various diseases. With the rapid development of POC(point-of-care) systems, a convenient house-using urinalysis device is widely needed. However, considering the difference of onboard systems and multiple test indicators in urinalysis, the design of such an intelligent device is still challenging. In this paper, a smartphone-based portable urinalysis system has been developed and applied for the colorimetric analysis of routine urine examination indices using an Android app. By integrating the test paper sensor in the portable device for urinalysis,our system significantly improves the instability of conventional dipstick-based manual colorimetry, and the smartphone application used for color discrimination enhances the accuracy of the visual assessment of sample strips. Using a simple operation approach that takes ~ 2 min per test, our system can be applied as rapid urinalysis for routine check-ups.作为最常见的医学诊断方法,尿液分析是一种用于筛查测试或日常监测各种疾病的高需求技术。随着POC (point-of-care)即时医疗系统的快速发展,人们广泛需要一种方便的家用尿液分析设备。然而,考虑到机载系统的差异以及尿液分析中的多项测试指标,这样智能设备的设计仍然具有挑战性。在本文中,开发了一种基于智能手机的便携式尿液分析系统,并将其应用于Android程序进行尿液常规检查中的指标比色分析。通过在便携式尿液分析设备中集成试纸传感器,我们的系统显着改善了传统基于试纸的手动比色法的不稳定性,用于颜色辨别的智能手机应用程序提高了样品条视觉评估的准确性。以简单的操作方法和每次约2 min的测试,我们的系统可应用于尿液的常规检查和快速分析。

关 键 词：urinalysis device COLORIMETRY diagnostic imaging POINT-OF-CARE SMARTPHONE 

分 类 号：R318.6[医药卫生—生物医学工程]