Surges of hospital-based rhinovirus infection during the 2020 coronavirus disease-19(COVID-19)pandemic in Beijing,China  

作　　者：Ruo-Xi Zhang Dong-Mei Chen Yuan Qian Yu Sun Ru-Nan Zhu Fang Wang Ya-Xin Ding Qi Guo Yu-Tong Zhou Dong Qu Ling Cao Chun-Mei Zhu Lin-Qing Zhao 

机构地区：[1]Laboratory of Virology,Beijing Key Laboratory of Etiology of Viral Diseases in Children,Capital Institute of Pediatrics,Beijing 100020,China [2]Intensive Care Unit,Affiliated Children's Hospital,Capital Institute of Pediatrics,Beijing 100020,China [3]Department of Respiratory,Affiliated Children's Hospital,Capital Institute of Pediatrics,Beijing 100020,China

出　　处：《World Journal of Pediatrics》2021年第6期590-596,共7页世界儿科杂志（英文版）

基　　金：This work was supported by grants from The Pediatric Medical Coordinated Development Center of the Beijing Hospitals Authority(No.XTZD20180505);Beijing Municipal Commission of Health and Family(No.2060399 PXM2017_026268_00005_00254486).

摘　　要：Background A series of public health preventive measures has been widely implemented in Beijing to control the corona-virus disease-19(COVID-19)pandemic since January 2020.An evaluation of the effects of these preventive measures on the spread of other respiratory viruses is necessary.Methods Respiratory specimens collected from children with acute respiratory infections were tested by NxTAGTN,respiratory pathogen panel assays during January 2017 and December 2020.Specimens characterized as rhinoviruses(RVs)were sequenced to identify the RV species and types.Then,the epidemiology results of respiratory pathogens in 2020 were compared with those from 2017 to 2019 using SPSS statistics 22.0.Results The positive rates of adenovirus(ADV),influenza virus(flu),RVs,and respiratory syncytial virus(RSV)dropped abruptly by 86.31%,94.679c,94.59%,and 92.17%,respectively,from February to May 2020,compared with the average level in the same period during 2017-2019.Positive rates of RVs then steeply increased from June 2020(13.77%),to an apex(37.25%)in August 2020,significantly higher than the average rates(22.51%)in August 2017-2019(7^=0.005).The increase,especially in group>3 years,was accompanied by the reopening of schools and kindergartens after the 23rd and 24th week of 2020 in Beijing.Conclusions Whereas the abrupt drop in viral pathogen positive rates from February to May 2020 revealed the remarkable effects of the COVID-19 preventive measures,the sharp increase in positive rates of RVs from the 23rd week of 2020 might be explained by the reopening of schools and kindergartens in Beijing.

关 键 词：Children Coronavirus disease-19(COVID-19) Human rhinovirus Preventive measures Respiratory viruses 

分 类 号：R726[医药卫生—儿科]