Evaluation of a new frequency-volume chart for children with primary monosymptomatic nocturnal enuresis:a prospective,comparative study  

作　　者：Jing-Jing Wang Dong-Jie Wang Hai-Dong Fu De-Xuan Wang Qing Yang Xiao-Jie Peng Rui Fu Huan-Dan Yang Rui-Feng Zhang Xiao-Wen Wang Jiang-Wei Luan Fei Zhao Qiu-Xia Chen Fang-Fang Liang Lu Cao Jian-Jiang Zhang Ying-Jie Li Yang Dong Hui-Mei Huang Ying Bao Xiao-Yu Shen Wei Zhou Guang-Hai Cao Cui-Hua Liu Yan-Yan Jin Mei-Lin Ma Li Jiang Qian Shen Hong Xu Jian-Hua Mao 

机构地区：[1]Department of Nephrology,TChildren's Hospital of Zhejiang University School of Medicine,National Clinical Research Center of Child Health,Hangzhou,China [2]Department of Nephrology,The Second Attiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University,Wenzhou,China [3]Department of Nephrology,Jiangxi Provincial Children's Hospital,Nanchang,China [4]Department of Nephrology,Xuzhou Children's Hospital,Xuzhou Medical University,Xuzhou,China [5]Department of Nephrology,Wuhan Children's Hospital(Wuhan Maternal and Child Healthcare Hospital),Tongji Medical College,Huazhong University of Science and Technology,Wuhan,China [6]Department of Nephrology,Children's Hospital of Nanjing Medical University,Nanjing,China [7]Department of Rheumatology,Shenzhen Children's Hospital,Shenzhen,China [8]Department of Pediatrics,The First Affiliated Hospital of Zhengzhou University,Zhengzhou,Henan,China [9]Department of Nephrology,Guangzhou Women and Children's Medical Center,Guangzhou,China [10]Department of Nephrology,Anhui Provincial Children's Hospital,Hefei,China [11]Department of Nephrology,The Affiliated Children Hospital of Xi'an Jiaotong University,Xi'an,China [12]Department of Nephrology,Shanghai Children's Medical Center,Shanghai,China [13]Department of Nephrology and Rheumatology,Children's Hospital Affiliated to ZhengZhou University,Henan Children's Hospital,ZhengZhou Children's Hospital,ZhengZhou,China [14]Medical Affairs Department,Ferring Pharmaceuticals(Asia)Company Limited,Shanghai,China [15]Marketing Department,Ferring Pharmaceuticals(Asia)Company Limited,Shanghai,China [16]Department of Nephrology,The Children's Hospital of Fudan University,Shanghai,China

出　　处：《World Journal of Pediatrics》2021年第6期643-652,共10页世界儿科杂志（英文版）

基　　金：funding from the National Natural Foundation of China(81770710);Key Research and Development Plan of Zhejiang Province(2019C03028);the Major projects jointly constructed by the Zhejiang province and National Health Commission(WKJ-ZJ-1908);the Natural Science Foundation of Zhejiang Province(LQ18H050001).

摘　　要：Introduction To improve compliance with voiding diaries in children with primary monosymptomatic nocturnal enuresis(PMNE),a new modified 3-day weekend frequency-volume chart(FVC)was designed,and the compliance and validity of this modified FVC was evaluated by comparing with the International Children's Continence Society(ICCS)recommended voiding diary.Methods A total of 1200 patients with PMNE were enrolled in the study from 13 centers in China and were randomly assigned to record this modified FVC or the ICCS-recommended voiding diary.The primary outcome measure was the compliance,assessed by comparing the completing index and the quality score of diaries between two groups.The secondary outcome measure was the validity,evaluated by comparing the constituent of subtypes,micturition parameters and response rate to desmopressin.Results Among the 1200 participants enrolled in the study,447 patients completed the ICCS-recommended voiding diary and 469 completed the modified diary.The diurnal completing index and the quality score of the modified FVC group were better than those of the ICCS group.In addition,there was no significant difference between these two groups in the subtype classification,or in the response rate to desmopressin.Conclusions The modified FVC could be applied to obtain the voiding characteristics of children with PMNE as the ICCS-recommended voiding diary does and offers a reasonable and better choice for children with PMNE from the unselected population in the future.

关 键 词：CHILDREN COMPLIANCE Nocturnal enuresis Voiding diary 

分 类 号：R726.9[医药卫生—儿科]