亚胺类共价有机骨架材料在样品前处理中的应用  

Application of imine covalent organic frameworks in sample pretreatment

作　　者：袁红梅 卢泽毅 李玉凰 张成江 李攻科[2] YUAN Hongmei;LU Zeyi;LI Yuhuang;ZHANG Chengjiang;LI Gongke(School of Pharmacy, Zunyi Medical University, Zunyi 563000, China;School of Chemistry, Sun Yat-sen University, Guangzhou 510275, China)

机构地区：[1]遵义医科大学药学院,贵州遵义563000 [2]中山大学化学学院,广东广州510275

出　　处：《色谱》2022年第2期109-122,共14页Chinese Journal of Chromatography

基　　金：国家自然科学基金(21765027);贵州省自然科学基金(黔科合基础2018[1188]);遵义医科大学博士基金(F-817).

摘　　要：亚胺类共价有机骨架(I-COFs)是有机单体根据席夫碱(Schiff-base)反应原理缩合形成的一类新型多孔晶体有机材料。I-COFs具有骨架密度低、比表面积大、孔隙率高、单体种类丰富、孔径尺寸可控、结构可功能化、合成方法多样和物化稳定性好等优点。近年来,I-COFs已成为材料科学领域的研究前沿,并广泛用于气体吸附、存储、催化、传感、光电材料等方面。I-COFs材料优异的物理化学性能使其非常适于用作复杂样品中痕量目标物的分离富集介质,其高比表面积、高孔隙率性能赋予了它极高的吸附负载量,这些性能使得目标分析物可被高效富集;通过控制有机单体的链段长度、几何结构、掺杂元素、取代基团等方面精确调控I-COFs的孔洞结构和功能化基团,从而实现目标痕量物质的选择性富集。目前,I-COFs材料在样品前处理领域作为新型萃取介质已引起了极大关注。该文综述了近年来I-COFs材料的主要类型、合成方法及其在固相萃取、磁性固相萃取、分散固相萃取和固相微萃取方面的研究进展,同时展望了I-COFs在样品前处理领域的发展前景。Imine covalent organic frameworks(I-COFs),including imine-linked COFs and hydrazone-linked COFs,are a new type of crystalline porous organic materials constructed by the condensation of organic monomers by the Schiff-base reaction.Because they are composed of lightweight elements linked by strong covalent bonds,I-COF materials possess the advantages of low skeleton density,large surface area,high porosity,abundant monomer species,controllable pore size,functionalized structure,diverse synthetic methods,excellent adsorption performance,outstanding physical and chemical stabilities,etc.In recent years,interest in the field of I-COFs has increased tremendously because of their exceptional performance and broad applications in gas storage,gas separation,catalysis,sensing,photoelectric materials,sample pretreatment,drug delivery,and other fields.To date,imine bonds are one of the most widely used covalent bonds in COFs,and represent one of the most important ways to obtain I-COFs with excellent chemical stabilities.The synthesis methods for I-COFs include solvothermal synthesis,microwave synthesis,mechanochemical grinding synthesis,and room-temperature synthesis methods.Solvothermal synthesis is the most extensively used method for the production of I-COFs with high specific surface areas and good thermal stabilities.The microwave synthesis method is conducive to the rapid synthesis of COFs in industry,providing a more time-saving,simpler,and safer route for large-scale preparation of I-COFs.The mechanochemical grinding synthesis of porous solids has gained importance as an alternative to conventional solvothermal synthesis,because the process is quick,environment-friendly,and potentially scalable.The room-temperature method is characterized by mild reaction conditions and rapid reactions.It is an energy-saving,economic,safe,and green synthesis method,which has emerged as a hot spot in the preparation of I-COFs in recent years.Research progress over the past years on the application of I-COFs in the field of materials

关 键 词：亚胺类 共价有机骨架 样品前处理 综述 

分 类 号：O658[理学—分析化学]