体育领域热点--克仑特罗检测方法研究近况及发展方向  

Hot Spot in Sports——Review on Determination Methods and Development Direction of Clenbuterol

作　　者：张建丽 ZHANG Jian-li(China Institute of Sport Science,General Administration of Sport of China,Beijing 100061,China)

机构地区：[1]国家体育总局体育科学研究所,北京100061

出　　处：《分析测试学报》2022年第1期63-70,共8页Journal of Instrumental Analysis

摘　　要：克仑特罗在临床上主要用于治疗哮喘,但由于其同时又具有蛋白同化作用,因此也被非法滥用于畜牧业和体育领域。畜牧业中的滥用现象会导致该药物在动物肌肉或其他可食性组织中残留,误食此类肉食品会引发运动员兴奋剂尿检阳性事件。2014年以来,克仑特罗每年的阳性检出例数一直位居当年所有阳性物质之首,其中绝大多数阳性均与误食克仑特罗污染的肉食品有关。如何区分兴奋剂检测领域食源性和药源性克仑特罗已成为一项国际性难题。克仑特罗也因此再次成为体育领域的关注热点。该文通过查阅近十年文献资料,总结分析了克仑特罗的检测方法和在体育领域的滥用现象及应对方法,意在全面梳理该药物的检测方法研究进展及其在体育领域的滥用现状,为今后进一步开展相关工作奠定基础。Clenbuterol is mainly used to treat asthma clinically,but it is also illegally abused in ani⁃mal husbandry and sports due to its anabolic effect.The abuse in animal husbandry will lead to the residue of the drug in animal muscle or other edible tissues.Ingestion of this kind of contaminated meat by mistake will trigger the positive event of doping control.The number of positive cases of clen⁃buterol has been at the top of positive substances list every year since 2014,and the vast majority of positive cases are related to the accidental consumption of meat food contaminated by clenbuterol.How to distinguish whether it is food contamination or doping abuse of clenbuterol in doping control has been an international problem.Therefore,clenbuterol has once again become a hot spot in sports.In order to comprehensively sort out the research progress of the determination methods for clenbuter⁃ol and its development direction in sports,laying a foundation for further related work in the future,the determination methods of clenbuterol and its abuse in sports are summarized through consulting the literatures in recent ten years.

关 键 词：克仑特罗 蛋白同化作用 兴奋剂 检测方法 

分 类 号：O657.63[理学—分析化学] G353.11[理学—化学]