新型冠状病毒肺炎患者沉默性低氧血症的发生机制  

Mechanism of silent hypoxemia in COVID-19 patients

作　　者：刘露[1] 于世寰[1] Liu Lu;Yu Shihuan(Department of Respiratory Medicine,the First Affiliated Hospital of Harbin Medical University,Harbin 150001,China)

机构地区：[1]哈尔滨医科大学附属第一医院呼吸内科,哈尔滨150001

出　　处：《国际呼吸杂志》2022年第1期23-26,共4页International Journal of Respiration

摘　　要：新型冠状病毒肺炎给医疗服务带来了沉重负担, 严重威胁人类健康。临床表现主要包括发热、干咳、呼吸困难等。一些新型冠状病毒肺炎患者虽然血氧饱和度已经很低, 但其本身并无明显的呼吸困难等不适, 被称为"沉默性低氧血症"。这部分患者的病情可能会发生突然而快速的恶化, 出现急性呼吸窘迫综合征等情况, 危及生命。及早识别这一部分患者, 并对其进行积极治疗, 可能会更好地判断是否对其使用辅助通气治疗, 进而降低患者的病死率。文章对新型冠状病毒肺炎患者沉默性低氧血症的发病机制进行综述, 以便对患者进行更有效的治疗。The coronavirus disease 2019(COVID-19)seriously threatens human health which also brought heavy burden to patients and Health system.The clinical manifestations mainly include fever,dry cough,and dyspnea.COVID-19 patients who have very low blood oxygen saturation but no obvious discomfort such as dyspnea are called"silent hypoxemia".The condition of these patients may suddenly deteriorate,with acute respiratory distress syndrome(ARDS),etc.,severe cases can be life-threatening.Therefore,early identification and active treatment for silent hypoxemia in COVID-19 will help be better to determine whether to use assisted ventilation treatment,thereby reducing the mortality.The purpose of this article is to review the mechanism of silent hypoxemia in COVID-19 patients to provide more effective treatment for patients.

关 键 词：冠状病毒感染 新型冠状病毒肺炎 沉默性低氧血症 

分 类 号：R563.1[医药卫生—呼吸系统]