Molecular Detection and Identification of Candidatus Ehrlichia Hainanensis,A Novel Ehrlichia Species in Rodents from Hainan Province,China  

作　　者：ZHAO Hong Qing LIU Pei Pei XUE Feng LU Miao QIN Xin Cheng LI Kun 

机构地区：[1]National Institute for Communicable Disease Control and Prevention,Chinese Center for Disease Control and Prevention,Beijing 102206,China [2]Chinese Center for Disease Control and Prevention,Beijing 102206,China [3]Zhejiang Mariculture Research Institute,Wenzhou 325000,Zhejiang,China

出　　处：《Biomedical and Environmental Sciences》2021年第12期1020-1023,共4页生物医学与环境科学（英文版）

基　　金：funded by the National Important Scientific&Technology Project [2018ZX10101002-002 and2018ZX10732401-001];the Inner Mongolia Natural Science[grant No. 2016MS0859];the Key Scientific and Technology Project of Inner Mongolia Autonomous Region [grant No. 2021ZD0006];the National Natural Science Foundation of China [grant No. 82102390]。

摘　　要：Ehrlichia(Anaplasmataceae family)are obligatory intracellular bacteria that infect humans and animals.They are hosted by mammals such as canines,bovines and wild rodents,and are vectored by ticks.In this study,we collected 121 rodent samples comprising 67 Niviventer fulvescens,27 Rattus tanezumi,24 Chiromyscus sp.,2 Rattus nitidus and 1 Leopoldamys edwardsi from Hainan province,which includes the second largest island in China.The presence and genetic diversity of Ehrlichia species was evaluated and characterized by amplification and sequencing of 16S rRNA,groEL and gltA genes.An Ehrlichia species was detected in 5 of the 67 Niviventer fulvescens samples(7.46%).The 16S rRNA,groEL and gltA genes showed the highest identity to known Ehrlichia sequences(99.20%,89.87%and 83.86%,respectively).In the phylogenetic trees they formed a cluster distinct from all other species.We propose that this species is a putative novel Ehrlichia species,which we suggest be named Candidatus Ehrlichia hainanensis.Its pathogenicity to humans remains to be further researched,and molecular surveillance in local populations is needed.

关 键 词：Candidatus Ehrlichia hainanensis Hainan province Niviventer fulvescens 

分 类 号：R378[医药卫生—病原生物学]