卵胞浆内单精子显微注射完全受精失败的原因和处理对策  

Total fertilization failure after intracytoplasmic sperm injection: the cause and clinical treatment

作　　者：黄莹(综述) 胡少飞(审校)[1] HUANG Ying;HU Shao-fei(Reproductive Center,Nanning Maternity and Child Health Hospital,Nanning 530011,Guangxi,CHINA)

机构地区：[1]南宁市妇幼保健院生殖医学中心,广西南宁530011

出　　处：《海南医学》2022年第2期247-249,共3页Hainan Medical Journal

摘　　要：卵胞浆内单精子注射(ICSI)中发生完全受精失败(TFF)的发生率是1%~4%。发生ICSI-TFF的原因可能是卵母细胞激活失败、卵子质量差、精子异常、ICSI的实验室技术和环境等,临床对策有卵母细胞人工激活、形态学选择性单精子卵胞浆内显微注射、优化促排卵方案、供精或供卵等。本文对ICSI-TFF发生可能的原因及临床对策进行了综述。The incidence of total fertilization failure(TFF) after intracytoplasmic sperm injection(ICSI) is 1%to 4%. The causes of ICSI-TFF may be the failure of oocyte activation, poor oocyte quality, sperm abnormalities, ICSI laboratory techniques and environment. Clinical treatments include artificial oocyte activation, morphologically selective intracytoplasmic sperm microinjection, optimization of ovulation promotion protocols, sperm or oocyte donation. The paper reviews the possible cause and clinical treatment of ICSI-TFF.

关 键 词：卵胞浆内单精子注射 完全受精失败 卵母细胞激活失败 卵母细胞人工激活 综述 

分 类 号：R699[医药卫生—泌尿科学]