盐酸戊乙奎醚注射液联合新斯的明在腹腔镜术后抗残余肌松不良的效果观察  

Observation on the effect of penehyclidine hydrochloride injection combined with neostigmine in the treatment of residual muscular dysrelaxation after laparoscopic operation

作　　者：张文婷[1] 周勇[1] 巫志国[1] ZHANG Wenting;ZHOU Yong;WU Zhiguo(Department of Anesthesiology,Pingxiang People's Hospital,Pingxiang,Jiangxi,337055,China)

机构地区：[1]萍乡市人民医院麻醉科,江西萍乡337055

出　　处：《当代医学》2022年第3期56-58,共3页Contemporary Medicine

摘　　要：目的探究盐酸戊乙奎醚注射液联合新斯的明在腹腔镜术后抗残余肌松不良的效果。方法选取本院2020年6月至2021年6月收治的56例行腹腔镜下胆囊切除手术治疗的患者,根据电脑随机盲选法分为治疗组和对照组,每组28例。两组采用相同麻醉诱导和麻醉维持方法,术后以实时肌松监测仪监测肌松状态。对照组不进行其他处理,治疗组在对照组基础上采用盐酸戊乙奎醚注射液配伍新斯的明实施肌松拮抗。比较两组不同刺激点肌肉松弛状态及麻醉苏醒时间指标(意识恢复时间、拔管时间及定向力恢复时间)。结果治疗组在TOF 0.7、TOF 0.9及TOF 1.0时肌肉恢复时间均短于对照组(P<0.05)。治疗组意识恢复时间、拔管时间、定向力恢复时间均短于对照组(P<0.05)。结论盐酸戊乙奎醚注射液联合新斯的明在腹腔镜术后抗残余肌松不良的效果确切,可促进肌肉状态恢复,缩短康复进程,值得临床推广应用。Objective To explore the effect of penehyclidine hydrochloride injection combined with neostigmine in the treatment of residual muscular dysrelaxation after laparoscopic surgery. Methods 56 patients who received laparoscopic cholecystectomy surgery from June 2020 to June2021 in our hospital were randomly selected and they were divided into treatment group and control group, with 28 cases in each group. The same anesthesia induction and maintenance methods were used in the two groups. The control group didn’ t give any other treatment, and the treatment group was given penehyclidine hydrochloride injection combined with neosmin on the basis of the control group. The state of muscle relaxation at different stimulation points and the time index of anesthesia recovery(consciousness recovery time, extubation time and directional force recovery time) were compared between the two groups. Results The muscle recovery time of the treatment group was shorter than that of the control group at TOF 0.7,TOF 0.9 and TOF 1.0(P<0.05). The recovery time of consciousness, extubation time, and the recovery time of directional force in the treatment group were shorter than those in the control group(P<0.05). Conclusion The effect of penehyclidine hydrochloride injection combined with neostigmine in the treatment of residual muscular dysrelaxation after laparoscopic surgery is accurate, which can promote the recovery of muscle state and shorten the rehabilitation process, and it is worthy of clinical application.

关 键 词：腹腔镜 新斯的明 盐酸戊乙奎醚注射液 残余肌松不良 

分 类 号：R614[医药卫生—麻醉学]