屈光参差性弱视与斜视性弱视临床疗效的比较  

Comparison of clinical efficacy effect between anisometropia amblyopia and strabismus amblyopia

作　　者：王家凤 刘贺婷[1] 陶黎明[1] Jia-Feng Wang;He-Ting Liu;Li-Ming Tao(Department of Ophthalmology, Second Affiliated Hospital, Anhui Medical University, Hefei 230601, Anhui Province, China)

机构地区：[1]安徽医科大学第二附属医院眼科,中国安徽省合肥市230601

出　　处：《国际眼科杂志》2022年第2期211-214,共4页International Eye Science

基　　金：2021年度安徽省高校自然科学研究项目(No.KJ2021A0328)。

摘　　要：目的:分析比较屈光参差性与斜视性弱视的治疗效果。方法:前瞻性研究。2018-07/2020-01在我院门诊确诊的并首次接受治疗的单眼弱视患者46例,平均年龄9±3岁,其中男26例,女20例,按照临床诊断分为斜视性弱视组(无屈光不正),共23例,平均年龄9±3岁,其中男12例,女11例。以及屈光参差性弱视组,共23例,平均年龄9±3岁,其中男14例,女9例。对两组患者采用遮盖及精细训练治疗弱视,于治疗前及治疗后采用国际标准视力表检测视力、用Titmus图谱行立体视锐度的检测。比较两组患者经弱视治疗前后最佳矫正视力及立体视恢复的差异。结果:治疗前两组患者弱视眼的最佳矫正视力无差异(t=-0.475,P>0.05),但斜视性弱视患者的立体视功能明显低于屈光参差性弱视患者(t=-3.919,P<0.001);通过2mo的治疗,两组患者最佳矫正视力提高值有明显差异(t=-2.946,P<0.01),而两组患者立体视提高值无差异(t=1.305,P>0.05);通过6mo的治疗,两组患者最佳矫正视力提高差值有明显差异(t=-2.353,P<0.05),两组患者立体视提高差值也有明显差异(t=2.218,P<0.05);但在6mo时斜视性弱视患者的立体视水平仍低于屈光参差性弱视患者(t=-2.760,P<0.01)。结论:治疗前视力相同的斜视性弱视与屈光参差性弱视,斜视性弱视患者的立体视功能损伤更重。通过治疗,屈光参差性弱视患者的视力恢复较快,而斜视性弱视患者的立体视功能恢复较快,但其立体视功能水平仍低于屈光参差性弱视患者。AIM:To compare the effect of comprehensive treatment in children with anisometropia and strabismus amblyopia.METHODS:Prospective study.Forty-six individuals(mean age 9±3 years old,26 males,20 females)with previously untreated monocular amblyopia were recruited in our hospital from July 2018 to January 2020.There were 23 patients with strabismus monocular amblyopia(mean age 9±3 years old,12 males,11 females)and 23 patients with anisometropia monocular amblyopia(mean age 9±3 years old,14 males,9 females).The best corrected visual acuity(Tumbling E Chart)and stereopsis(Titmus)were measured before and after a 6mo period of comprehensive treatment(refractive correction,patching and precision eyesight training).The differences of monocular visual benefits(visual acuity)and binocular visual benefits(stereopsis)between two groups before and after treatment were compared.RESULTS:Before treatment,there was no significant difference of best corrected visual acuity between anisometropia amblyopia and strabismus amblyopia(t=-0.475,P>0.05),but the stereopsis of strabismus amblyopia was significantly lower than that of anisometropia amblyopia(t=-3.919,P<0.001).After 2mo treatment,there was a significant difference in best corrected visual acuity benefits between anisometropia amblyopia and strabismus amblyopia(t=-2.946,P<0.01),but there was no significant difference in stereopsis benefits between anisometropia amblyopia and strabismus amblyopia(t=1.305,P>0.05).After 6mo treatment,there was a significant difference in visual acuity benefits between anisometropia amblyopia and strabismus amblyopia(t=-2.353,P<0.05),and there was also a significant difference in stereopsis benefits between anisometropia amblyopia and strabismus amblyopia(t=2.218,P<0.05).However,the stereopsis of strabismus amblyopia was still lower than that of anisometropia amblyopia at 6mo(t=-2.760,P<0.01).CONCLUSION:We conclude that the stereopsis of patients with strabismus amblyopia is more severe than those with anisometropic amblyopia before treatment und

关 键 词：屈光参差 斜视 弱视 立体视 遮盖治疗 效果 

分 类 号：R47[医药卫生—护理学]