A Systematic Review and Meta-Analysis on Gualou Niubang Decoction for Acute Mastitis  

作　　者：Tian-tian Gao Shuo Zhang Zhen-lin Chen Miao Wang Hong-yan Wang Wen-jing Ma Lu Wang 

机构地区：[1]Shannxi University of Chinese Medicine,Xianyang 712046,Shannxi Province,China [2]Beijing University of Chinese Medicine,Beijing 100029,China [3]The Second Affiliated Hospital of Shannxi University of Chinese Medicine,Xianyang 712000,Shannxi Province,China

出　　处：《Journal of Clinical and Nursing Research》2022年第1期59-66,共8页临床护理研究（英文）

基　　金：General Project of the National Natural Science Foundation of China(No.81974584)。

摘　　要：Objective:To systematically evaluate the clinical efficacy of Gualou Niubang decoction in the treatment of acute mastitis.Methods:Randomized controlled trials of Gualou Niubang decoction in the treatment of acute mastitis included in PubMed,Springer,Embase,Cochrane Library,CNKI,Wanfang,Weipu,and China Biomedical Literature Database from January 2016 to present.The Cochrane risk bias assessment tool was used to evaluate the risk of bias.Used Revman 5.3 software for Meta analysis.Results:There are 8 articles that meet the inclusion criteria,comprising 919 subjects,the test group were 462,cases and control group were 457 cases.The results of statistical analysis showed that the clinical efficacy of the experimental group was significantly higher than which of the control group,[RR=1.19,95%CI(1.07,1.33),P=0.002],the difference was statistically significant.Among the secondary outcome indicators,compared to the control group,Gualou Niubang decoction can effectively relieve the main symptoms of acute mastitis[MD=-1.96,95%CI(-2.27,-1.65),P<0.0001].Gualou Niubang decoction combined with antibiotics can shorten the length of hospital stay[MD=-5.23,95%CI(-6.02,-4.44),P<0.00001]and reduce white blood cell count[MD=-2.40,95%CI(-4.71,-0.08),P=0.04]are better than antibiotics.Conclusion:The use of Gualou Niubang decoction to treat acute mastitis can not only improve clinical efficacy,but also effectively relieve clinical symptoms,shorten hospital stay and reduce white blood cell count.

关 键 词：Gualou Niubang decoction Acute mammary mastitis Milk carbuncle Meta analysis 

分 类 号：R28[医药卫生—中药学]