梅毒性脱发合并HIV感染1例  

Alopecia of a syphilis patient with HIV co-infected patient: a case report

作　　者：薛紫 罗颖 何仁亮 XUE Zi;LUO Ying;HE Renliang(Dermatology Hospital,Southern Medical University,Guangzhou 510091,China)

机构地区：[1]南方医科大学皮肤病医院,广东广州510091

出　　处：《皮肤性病诊疗学杂志》2021年第6期461-464,共4页Journal of Diagnosis and Therapy on Dermato-venereology

摘　　要：报告1例梅毒性脱发合并HIV感染。患者男,44岁,弥漫性斑状脱发伴白发增多11个月余。查体可见前额发际线"M型"上移,全头散在圆形、类圆形脱发斑,边界欠清,白发增多,拉发试验(-),双手掌、足底红斑、鳞屑。头皮脱发斑处皮肤镜检查示:头皮无毛区内毛囊开口存在,毛干变细,少量黑点。实验室检查:TRUST定性(+),TRUST定量(1∶128),TPPA试验>1∶1 280,HIV抗体(+)。头皮脱发区病理组织活检示:真皮毛囊周围少量淋巴组织细胞,见休止期毛囊,周围纤维包绕,毛球部见浆细胞。诊断:梅毒性脱发合并HIV感染。经青霉素治疗5个月后,脱发斑消退,手足红斑、鳞屑消失,无再发脱发斑。A 44-year-old Chinese man had hair loss and increasing gray hair for 11 months. Physical examination showed "M" pattern frontal hair line, multiple small hair loss patches on scalp with indistinct boundary and increasing gray hair, pull hair test was negative. Diffused erythema and scale appeared on both his palm and pelam. Dermoscope revealed hair follicular orifice existed, diminution of hair shaft and few black dots. Laboratory examination showed syphilis and HIV co-infected. Scalp biopsy specimen revealed mild lymphocytes infiltration around hair follicle in dermal, some of which had a peribulbar plasmocyte infiltrate, several terminal hair follicles were surrounded by fibrous tissue. The patient was diagnosed as syphilitic alopecia and HIV co-infected, and accepted treatment with penicillin. After 5 months treatment, new hair grew up in former hair loss patches, and diffused erythema on limp skin disappeared.

关 键 词：梅毒性脱发 HIV感染 皮肤镜 诊断 

分 类 号：R759.1[医药卫生—皮肤病学与性病学] R512.91[医药卫生—临床医学] R758.71