拟康定乌头中二萜生物碱成分及拒食活性  

Diterpenoid alkaloids from Aconitum rockii and their antifeedant activity

作　　者：任佳俐 程瑞翔 王腾飞 陈琳[1] 周先礼[1] 黄帅[1] REN Jia-li;CHENG Rui-xiang;WANG Teng-fei;CHEN Lin;ZHOU Xian-li;HUANG Shuai(School of Life Science and Engineering,Southwest Jiaotong University,Chengdu 610031,China)

机构地区：[1]西南交通大学生命科学与工程学院,成都610031

出　　处：《农药》2022年第1期51-56,共6页Agrochemicals

基　　金：国家自然科学基金(21807089)。

摘　　要：[目的]为了研究拟康定乌头中化学成分及其拒食活性。[方法]利用正反相硅胶柱层析进行分离纯化,结合HR-ESIMS、IR、1D和2D NMR等波谱技术对分离得到的化合物结构进行鉴定,采用叶碟法测试了其中10个化合物对甜菜夜蛾3龄幼虫的拒食活性。[结果]共分离得到15个二萜生物碱。其中10个化合物均存在一定的拒食活性。[结论]化合物的拒食活性强弱C;-型二萜生物碱>双二萜型二萜生物碱>C;-型二萜生物碱。[Aims] To study the chemical constituents and antifeeding activity of Aconitum rockii. [Methods] The compounds were isolated and purified by positive and reverse phase silica gel column chromatography. The structures of the compounds were identified by HR-ESIMS, IR, 1 D and 2 D NMR spectroscopic techniques. The antifeeding activities of tencompounds against the 3 rd instar larvae of Spodoptera exigua Hiibner were tested by leaf dish method.[Results] A total of 15 diterpene alkaloids were obtained. Ten compounds had certain antifeedant activity.[Conclusions] The order of antifeedant activity C;-diterpenoid alkaloids >bisditerpenoid alkaloids>C;-diterpenoid alkaloids.

关 键 词：毛茛科 乌头属 拟康定乌头 二萜生物碱 拒食活性 

分 类 号：TQ460[化学工程—制药化工]