幼年皮肌炎慢作用药物治疗进展  

Advances of slow-acting antirheumatic drug for juvenile dermatomyositis

作　　者：刘力[1] 孙艳茹 胡坚[1] LIU Li;SUN Yan-ru;HU Jian(Department of General Medicine(Immunology),Tianjin Children’s Hospital(Children’s Hospital of Tianjin University),Tianjin 300074,China;不详)

机构地区：[1]天津市儿童医院(天津大学儿童医院)综合内科(免疫),天津300074 [2]天津医科大学研究生院,天津300070

出　　处：《中国实用儿科杂志》2021年第11期839-842,共4页Chinese Journal of Practical Pediatrics

摘　　要：幼年皮肌炎是儿童少见的风湿性疾病之一,常用的治疗方案是激素联合慢作用药物。由于发病率较低,缺少大样本随机对照试验研究,选择哪种慢作用药物、了解药物之间的转换以及确定疗程是比较困难的。该文对治疗幼年皮肌炎的常用慢作用药物及其作用机制、剂量、不良反应和适应证进行介绍,有助于临床医师对药物选择进行权衡。Juvenile dermatomyositis is one of the rare rheumatic diseases in children.The common treatment is hormone combined with slow-acting drugs.It is difficult to choose slow-acting drugs,swith drugs and design course of treatment because of the low incidence and lack of large randomized controlled trials.The author summarizes the common slow-acting antirheumatic drugs used in the treatment of juvenile dermatomyositis,and introduces the mechanism of action,dosage,adverse reactions and indications of these drugs,in order to help doctors to select drugs.

关 键 词：幼年皮肌炎 慢作用抗风湿药物 治疗 

分 类 号：R72[医药卫生—儿科]