人参总皂苷糖果制剂的研制  

Studies of ginseng candy preparations

作　　者：王强 黄春明[1] 张治平[1] 于凤波 Wang Qiang;Huang Chunming;Zhang Zhiping;Yu Fengbo(Department of Plastic and Reconstructive Surgery,The People′s Hospital of Gaozhou,Guangdong 525200,China;Drug Clinical Institution,The People′s Hospital of Gaozhou,Guangdong 525200,China)

机构地区：[1]广东省高州市人民医院整形外科,525200 [2]广东省高州市人民医院药物临床机构办,525200

出　　处：《中国药物与临床》2022年第2期110-113,共4页Chinese Remedies & Clinics

基　　金：广东省茂名市科技计划项目(200330094559144);中国博士后科学基金(2021M692734)。

摘　　要：目的本实验开发了多种人参总皂苷糖果制剂,为人参功能性产品市场增加新品种。方法采用紫外分光光度法建立人参总皂苷糖果制剂质量检测标准。确定了压制糖果、硬糖和软糖的处方与制备工艺。以外观、硬度、干燥失重等作为考察指标,对人参总皂苷糖果制剂相关质量进行了检测。结果人参总皂苷在235 nm处有最大吸收,浓度在0.0244~0.1920 mg/ml浓度范围内线性关系良好。所制备的不同种类糖果制剂外观、硬度、干燥失重等各项指标均符合要求。结论本研究开发的人参总皂苷糖果制剂丰富了现有市场剂型。Objective The purpose of this article was aimed to prepared several ginseng candy preparations to improve the development of ginseng functional products.Methods The standard curve of ginseng preparations was established by UV spectrophotometry.The formulations and preparation processes of the ginseng pressed candy preparation,hard candy preparation and soft candy preparation were studied via orthogonal experiment.The appearance,hardness,dry weight loss,tablet weight and content were used as the inspection indicators,and the relevant quality of ginseng candy preparations were tested.Results The UV spectrophotometry results investigated that the maximum absorption wave of the ginseng was at 235 nm.Meanwhile,between the 0.0244~0.1920 mg/ml of the ginseng solutiongs possessed a good linear relationship at this wave.The appearance,hardness,loss on drying,tablet weight and content of the various types of candy preparations prepared met the standards.Conclusion The ginseng candy prepared in this study enriches the existing dosage forms.

关 键 词：人参皂苷类 糖果 剂型改进 

分 类 号：R283.6[医药卫生—中药学]