穿支皮瓣修复术治疗手外伤软组织缺损患者的效果  

Effects of perforator flap repair in treatment of hand injury patients with soft tissue defects

作　　者：胡建威 吕丰[1] HU Jianwei;LYU Feng(Hand Surgery Department of Central Hospital of Shenyang Medical College,Shenyang 110023 Liaoning,China)

机构地区：[1]沈阳医学院附属中心医院手外科,辽宁沈阳110023

出　　处：《中国民康医学》2022年第1期18-20,24,共4页Medical Journal of Chinese People’s Health

摘　　要：目的:观察穿支皮瓣修复术治疗手外伤软组织缺损患者的效果。方法:选取95例手外伤软组织缺损患者为研究对象,按随机数字表法将其分为对照组47例与研究组48例。对照组采用胸腹带蒂皮瓣修复术治疗,研究组采用穿支皮瓣修复术治疗,比较两组手外伤软组织缺损修复优良率、并发症发生率、抗菌药物使用时间、伤口愈合时间、住院时间、治疗前和治疗1周后炎性因子[白细胞介素-6(IL-6)、白细胞介素-8(IL-8)、肿瘤坏死因子-α(TNF-α)]水平和视觉模拟评分法(VAS)评分。结果:研究组手外伤软组织缺损修复优良率为95.84%(46/48),明显高于对照组的78.72%(37/47),差异有统计学意义(P<0.05);研究组并发症发生率为2.08%(1/48),明显低于对照组的17.02%(8/47),差异有统计学意义(P<0.05);研究组抗菌药物使用时间、伤口愈合时间和住院时间均短于对照组,差异有统计学意义(P<0.05);研究组IL-6、IL-8、TNF-α水平均低于对照组,差异有统计学意义(P<0.05);研究组VAS评分低于对照组,差异有统计学意义(P<0.05)。结论:穿支皮瓣修复术治疗手外伤软组织缺损患者可提高手外伤软组织缺损修复优良率,降低并发症发生率、炎性因子水平和VAS评分,以及缩短抗菌药物使用时间、伤口愈合时间和住院时间,其效果优于胸腹带蒂皮瓣修复术治疗。Objective:To observe effects of perforator flap repair in treatment of hand injury patients with soft tissue defects.Methods:95 patients with hand injuries and soft tissue defects were selected as the research objects,and were divided into control group of 47 cases and study group of 48 cases according to the random number table method.The control group was treated with thoracic-abdominal pedicle flap repair,while the study group was treated with perforator flap repair.The excellent and good rate of hand injury patients with soft tissue defects repair,the complication rate,the antibacterial drug use time,the wound healing time,the hospitalization time,the inflammatory factor levels before t and 1 week after the treatment[interleukin-6(IL-6),white blood cells Interleukin-8(IL-8),tumor necrosis factor-α(TNF-α)]levels and the visual analogue scale(VAS)score were compared between the two groups.Results:The excellent and good rate of hand injury patients with soft tissue defects repair in the study group was 95.84%(46/48),which was significantly higher than 78.72%(37/47)in the control group,and the difference was statistically significant(P<0.05).The incidence of adverse reactions in the study group was 2.08%(1/48),which was significantly lower than 17.02%(8/47)in the control group,and the difference was statistically significant(P<0.05).The antibacterial drug use time,the wound healing time and the hospitalization time in the study group were shorter than those in the control group,and the differences were statistically significant(P<0.05).The levels of IL-6,IL-8 and TNF-αin the study group were lower than those in the control group,and the differences were statistically significant(P<0.05).Further,the VAS score of the study group was lower than that of the control group,and the difference was statistically significant(P<0.05).Conclusions:Perforator flap repair in the treatment of the hand injury patients with soft tissue defects can increase the excellent and good rate of hand injury patients with soft tissue def

关 键 词：手外伤 软组织缺损 穿支皮瓣修复术 修复率 伤口愈合 VAS评分 炎性指标 

分 类 号：R658.2[医药卫生—外科学]