阻塞型睡眠呼吸暂停低通气综合征与代谢综合征相关性的研究进展  

Research progress on the relationship between obstructive sleep apnea hypopnea syndrome and metabolic syndrome

作　　者：朱良栋 刘洪林 赵丹[3] 叶贤伟[3] ZHU Liangdong;LIU Hongling;ZHAO Dan;YE Xianwe(Department of Respiratory and Critical Care Medicine,the First Affiliated Hospital of Hunan University of Medicine,Huaihua,Hunan 418000,P.R.China;Department of Respiratory and Critical Care Medicine,Guiqian International General Hospital,Guiyang,Guizhou 550002,P.R.China;Department of Respiratory and Critical Care Medicine,Guizhou Provincial People’s Hospital,Guiyang,Guizhou 550002,P.R.China)

机构地区：[1]湖南医药学院第一附属医院呼吸与危重症医学科,湖南怀化418000 [2]贵黔国际总医院呼吸与危重症医学科,贵阳550002 [3]贵州省人民医院呼吸与危重症医学科,贵阳550002

出　　处：《华西医学》2022年第1期116-119,共4页West China Medical Journal

基　　金：国家自然科学基金(81760013)。

摘　　要：近年来,越来越多的研究显示阻塞型睡眠呼吸暂停低通气综合征(obstructive sleep apnea hypopnea syndrome,OSAHS)与代谢综合征紧密联系且相互影响,而高血压、糖代谢异常、脂代谢紊乱、肥胖作为代谢综合征的主要组成成分更是被深入研究。持续气道正压通气是目前治疗OSAHS最主要的方法。该文就OSAHS与高血压、糖代谢异常、脂代谢紊乱、肥胖之间的关系及气道正压通气治疗效果进行综述,旨在为OSAHS合并代谢综合征的发病机制及治疗提供理论依据。In recent years,more and more studies have shown that obstructive sleep apnea hypopnea syndrome(OSAHS)and metabolic syndrome are closely related and interact with each other,while hypertension,abnormal glucose metabolism,lipid metabolism disorders and obesity,as the main components of metabolic syndrome,have been further studied.Continuous positive airway pressure is currently the main treatment for OSAHS.This review focuses on the association between OSAHS and hypertension,glucose metabolism abnormalities,lipid metabolism disorders,obesity and the effects of treatment with positive airway pressure,aiming to provide a theoretical basis for the pathogenesis and treatment of OSAHS complicated with metabolic syndrome.

关 键 词：阻塞型睡眠呼吸暂停低通气综合征 代谢综合征 高血压 

分 类 号：R589[医药卫生—内分泌] R766[医药卫生—内科学]