无创呼吸机间歇正压呼吸疗法对慢性阻塞性肺疾病并呼吸衰竭患者血气指标及通气情况的影响  

Effect of noninvasive ventilator intermittent positive pressure breathing therapy on blood gas index and ventilation in patients with chronic obstructive pulmonary disease and respiratory failure

作　　者：朱晓蓉 ZHU Xiaorong(Department of Respiratory and Critical Care Medicine,Ganzhou Fifth People′s Hospital,Jiangxi Province,Ganzhou341000,China)

机构地区：[1]江西省赣州市第五人民医院呼吸与危重症医学科,江西赣州341000

出　　处：《中国当代医药》2022年第3期52-55,共4页China Modern Medicine

基　　金：江西省赣州市指导性科技计划项目(GZ2016ZSF 233)。

摘　　要：目的探讨无创呼吸机间歇正压呼吸疗法对慢性阻塞性肺疾病并呼吸衰竭患者血气指标及通气情况的影响。方法选取2019年2月至2020年10月赣州市第五人民医院收治的84例慢性阻塞性肺疾病并呼吸衰竭患者为研究对象,采用随机数字表法将其分为对照组和观察组,各42例。对照组采用常规无创呼吸机持续通气,观察组采用无创呼吸机间歇正压呼吸疗法。比较两组患者的血气指标、并发症、心功能。结果两组患者治疗前的血气指标比较,差异无统计学意义(P>0.05);两组患者治疗后的血氧分压(PaO_(2))、血氧饱和度(SaO_(2))高于治疗前,动脉血二氧化碳分压(PaCO_(2))低于治疗前,差异有统计学意义(P<0.05);观察组治疗后的PaO_(2)、SaO_(2)高于对照组,PaCO_(2)低于对照组,差异有统计学意义(P<0.05)。两组患者治疗前的心功能指标比较,差异无统计学意义(P>0.05);两组患者治疗后左心射血分数(LVEF)高于治疗前,脑钠肽(BNP)低于治疗前,差异有统计学意义(P<0.05);观察组治疗后的LVEF高于对照组,BNP低于对照组,差异有统计学意义(P<0.05)。观察组的并发症总发生率低于对照组,差异有统计学意义(P<0.05)。结论慢性阻塞性肺疾病并呼吸衰竭患者采用无创呼吸机间歇正压呼吸疗法治疗不仅可改善患者血气指标,同时也可改善患者心功能,有效控制患者并发症。Objective To analyze the effect of noninvasive ventilator intermittent positive pressure breathing therapy on blood gas index and ventilation in patients with chronic obstructive pulmonary disease and respiratory failure.Methods A total of 84 patients with chronic obstructive pulmonary disease and respiratory failure admitted to Ganzhou Fifth People′s Hospital from February 2019 to October 2020 were selected as the research objects.They were randomly divided into the control group and the observation group,with 42 cases in each group.The control group was treated with conventional noninvasive ventilator continuous ventilation,and the observation group was treated with noninvasive ventilator intermittent positive pressure breathing therapy.The blood gas index,complications and cardiac function of the two groups were compared.Results There were no statistically significances in blood gas indexes between the two groups before treatment(P>0.05).After treatment,the partial pressure of oxygen(PaO_(2))and oxygen saturation(SaO_(2))in the two groups were higher than those before treatment,and partial pressure of carbon dioxide(PaCO_(2))in the arterial blood in the two groups were lower than those before treatment,the differences were statistically significant(P<0.05).After treatment,PaO_(2) and SaO_(2) in the observation group were higher than those in the control group,and PaCO_(2) was lower than that in the control group,the differences were statistically significant(P<0.05).There were no statistically significances in cardiac function indexes between the two groups before treatment(P>0.05).After treatment,the left ventricular ejection fraction(LVEF)of the two groups were higher than those before treatment,and the brain natriuretic peptide(BNP)was lower than that before treatment,the differences were statistically significant(P<0.05).The LVEF of the observation group after treatment was higher than that of the control group,and the BNP was lower than that of the control group,the differences were statistically signif

关 键 词：慢性阻塞性肺疾病 呼吸衰竭 无创呼吸机间歇正压呼吸疗法 血气指标 

分 类 号：R563.8[医药卫生—呼吸系统]