冠状动脉粥样硬化患者TG、AIP与冠状动脉病变严重程度的相关性分析  

Analysis on correlation between triglyceride and atherogenic index with severity of coronary arterial lesion in patients with coronary atherosclerosis

作　　者：刘正阳 张月兰[1] LIU Zhengyang;ZHANG Yuelan(Department of Cardiovascular Medicine,Fist Affiliated Hospital,China Medical University,Shenyang,Liaoning 110000,China)

机构地区：[1]中国医科大学附属第一医院心血管内科,沈阳110000

出　　处：《重庆医学》2022年第2期209-213,共5页Chongqing medicine

基　　金：国家科技部重点研发计划项目(2018YFC1312400)。

摘　　要：目的探讨冠状动脉粥样硬化患者甘油三酯(TG)、动脉粥样硬化指数(AIP)与冠状动脉病变严重程度的关系。方法纳入495例造影证实为冠脉粥样硬化患者,依据SYNTAX评分分为低、高分组。收集组间一般临床资料、TG、AIP等指标,分析各指标与SYNTAX评分之间的关系。结果SYNTAX评分高分组TG、AIP高于低分组,差异有统计学意义(P<0.05)。多因素logistic回归分析提示,高TG患者相对低TG患者,冠状动脉病变严重程度残余风险增加(OR=1.52,95%CI:1.15~2.00);高AIP患者相对低AIP患者,冠状动脉病变严重程度残余风险增加(OR=2.60,95%CI:1.90~3.56)。结论TG、AIP越高冠状动脉病变越严重。Objective To explore the relationship between triglyceride(TG),atherosclerosis index(AIP)and the severity of coronary arterial lesion in the patients with coronary atherosclerosis.Methods A total of 495 patients with coronary atherosclerosis confirmed by angiography were included and divided into the low score and high score groups according to the SYNTAX score.The general clinical data and the indicators such as TG and AIP were colleted in the two groups.The relationship between each index and SYNTAX score was analyzed.Results The TG and AIP levels of the high SYNTAX score group were higher than those in the low SYNTAX score group,and the difference was statistically significant(P<0.05).The multivariate logistic regression analysis indicated that the residual risk of coronary arterial lesion severity in the patients with high TG was increased compared with that in the patients with low TG(OR=1.52,95%CI:1.15-2.00).The residual risk of coronary arterial lesion severity in the patients with high AIP was increased compared with that in the patients with low AIP(OR=2.60,95%CI:1.90-3.56).Conclusion The higher the TG and AIP,the more severe the coronary artery lesion.

关 键 词：冠状动脉粥样硬化 SYNTAX评分 动脉硬化指数 甘油三酯 

分 类 号：R543[医药卫生—心血管疾病]