产前MRI对先天性心脏病胎儿心血管异常和脑发育的量化评估  

Quantitative MRI evaluation of cardiovascular abnormalities and brain in fetuses with congenital heart disease

作　　者：张霞[1] 董素贞(审校) ZHANG Xia;DONG Suzhen(Department of Radiology,Shanghai Children’s Medical Center,School of Medicine,Shanghai Jiao Tong University,Shanghai 200127,China)

机构地区：[1]上海交通大学医学院附属上海儿童医学中心放射科,上海200127

出　　处：《国际医学放射学杂志》2022年第1期71-74,共4页International Journal of Medical Radiology

基　　金：国家自然科学基金资助项目(81971582,81571628);上海市浦江人才计划项目(2019PJD030);上海市自然科学基金(19ZR1476700);上海市卫生和计划生育委员会科研课题(201540048)。

摘　　要：先天性心脏病(CHD)是影响胎儿生长发育的常见严重疾病,可以合并脑发育迟缓。MRI在胎儿发育定量评估中正逐渐成为超声以外的一种具有潜在价值的补充成像技术。就胎儿CHD与其脑发育的关系,以及产前MRI对CHD胎儿心血管和脑的结构、血流、氧合情况、脑成熟度及代谢情况量化评估的进展进行综述。Congenital heart disease is a common serious disease that affects the growth and development of the fetus.It can be associated with brain developmental delays.Magnetic resonance imaging(MRI)is gradually becoming a potentially valuable complementary imaging technique to ultrasound in quantitative evaluation of fetal development.This article reviews the relationship between fetal congenital heart disease and its brain development,the progress of prenatal MRI quantitative evaluation of the cardiovascular and brain structures,blood flow,oxygen saturation,brain maturity,and metabolism in the fetuses with congenital heart disease.

关 键 词：胎儿 先天性心脏病 脑发育 产前 磁共振成像 量化评估 

分 类 号：R714.5[医药卫生—妇产科学] R445.2[医药卫生—临床医学]