草食家畜母体营养对子代生命健康影响的研究进展  

Research Advances on Effects of Maternal Nutrition on Life Health of Offspring in Herbivorous Livestock

作　　者：赫晓娜 金鹿 李胜利 张春华 桑丹 张崇志 孙海洲 HE Xiao-na;JIN Lu;LI Sheng-li;ZHANG Chun-hua;Sangdan;ZHANG Chong-zhi;SUN Hai-zhou(College of Animal Science,Inner Mongolia Agricultural University,Hohhot 010018,China;Institute of Animal Nutrition and Feed,Inner Mongolia Academy of Agricultural and Animal Husbandry Sciences/Inner Mongolia Key Laboratory of Herbivores Nutrition,Hohhot 010031,China)

机构地区：[1]内蒙古农业大学动物科学学院,内蒙古呼和浩特010018 [2]内蒙古自治区农牧业科学院动物营养与饲料研究所/内蒙古自治区草食动物营养科学重点实验室,内蒙古呼和浩特010031

出　　处：《畜牧与饲料科学》2022年第1期31-38,共8页Animal Husbandry and Feed Science

基　　金：国家绒毛用羊产业技术体系(CARS-39-11);中央引导地方科技发展专项资金计划项目;鄂尔多斯市科技重大专项;内蒙古自治区“草原英才”工程产业创新人才团队;内蒙古自治区“草原英才”工程产业创新人才;内蒙古自治区草食动物营养科学重点实验室。

摘　　要：母体营养对胎儿基因表达的调节作用逐渐成为围产期生命营养科学研究的热点。妊娠期作为发育可塑性的关键窗口,甲基供体对胎儿发育的相关代谢基因起到修饰作用,表观遗传学可能涉及其中的分子机制。动物研究表明,母体营养供给不足或过剩都会限制胎儿的生长。结合国内外研究报道,探讨了草食家畜妊娠期母胎的营养需求、激素在稳态调节中发挥的作用以及妊娠期能量需求对妊娠健康的重要意义,概括了妊娠期草食动物营养在表观遗传学方面的研究进展,探讨了表观遗传相关技术在草食家畜育种中的应用,以期为制定草食动物妊娠期最佳营养策略、提高胚胎质量、培养高质量后代提供参考。The impacts of maternal nutrition on fetal gene expression has gradually become the focus in perinatal life nutrition research.The most important window of developmental plasticity is gestational period.Epigenetics may be implicated in the modification of metabolic genes associated with fetal development by methyl donors.In animal experiments,insufficient or excessive maternal nutrition has been proven to impede the fetal growth.By consulting the scientific reports abroad and in China,this paper discussed the maternal and fetal nutrition needs during gestational period,the roles of hormones in homeostasis regulation,and the importance of energy demands during gestational period on pregnancy health in herbivorous livestock.This paper also summarized the research progress of herbivores nutrition during gestational period in epigenetics,and discussed the application of epigenetic technologies in herbivorous livestock breeding,in hoping to provide references for formulating the best nutrition strategy for herbivores during gestational period,improving embryo quality,and breeding high-quality offspring.

关 键 词：胎儿 程序化发育 营养受限 表观遗传 

分 类 号：S814.1[农业科学—畜牧学]