特殊类型静脉畸形发病机制研究进展  

Research advances in the pathogenesis of special venous malformations

作　　者：陈昇 沈卫民[1] Chen Sheng;Shen Weiming(Department of Burns and Plastic Surgery,Children's Hospital of Nanjing Medical University,Nanjing 210008,China)

机构地区：[1]南京医科大学附属儿童医院烧伤整形科,南京210008

出　　处：《临床小儿外科杂志》2022年第1期89-92,共4页Journal of Clinical Pediatric Surgery

基　　金：南京市卫生科技发展专项基金(YKK20134)。

摘　　要：静脉畸形(venous malformation,VM)是最常见的血管畸形,根据其临床和组织学特征目前主要可分为普通静脉畸形和特殊类型静脉畸形。特殊类型静脉畸形主要包括家族性皮肤黏膜VM、蓝色橡皮乳头样痣(Bean)综合征、球形细胞VM等。除普通VM外,其余VM多伴有多个部位的病变。近年来随着基因测序技术的发展,关于这些特殊类型VM的文献报道逐渐增多。本文将对这些特殊类型的VM进行简要概述,并对其发病机制的研究进展进行综述。Venous malformation(VM)is the most common vascular malformation.According to its clinicohistological characteristics,it can be divided into common and special venous malformations.The latter type is composed of familial VM cutaneomucosal,blue rubber bleb nevus(Bean)syndrome and glomuvenous malformation.Except for common VM,most VMs are accompanied with multiple lesions.In recent years,with rapid developments of gene sequencing technology,a growing body of literature has elaborated upon special VMs.This review offered a brief overview of special VMs and summarized their pathogenetic mechanisms.

关 键 词：动静脉畸形/病因学 静脉/畸形 静脉/解剖学和组织学 

分 类 号：R725.4[医药卫生—儿科]