支气管热成形术在重症哮喘治疗中的临床应用  

Clinical Application of Bronchial Thermoforming in the Treatment of Severe Asthma

作　　者：吕锐[1] 冯亦伟[1] 陀子能[1] LV Rui;FENG Yi-wei;TUO Zi-neng(Gaozhou People's Hospital,Guangdong Gaozhou 525200)

机构地区：[1]高州市人民医院,广东高州525200

出　　处：《深圳中西医结合杂志》2021年第21期141-144,共4页Shenzhen Journal of Integrated Traditional Chinese and Western Medicine

摘　　要：目的:分析支气管热成形术在重症哮喘治疗中的应用效果。方法:选取高州市人民医院2019年1月至2021年1月期间收治的60例重症哮喘患者,随机将其均分为对照组和观察组,各30例。对照组给予常规治疗,观察组在对照组的基础上给予支气管热成形术治疗,比较两组临床疗效。结果:经治疗,观察组患者的哮喘发作急诊就诊频率、重度哮喘急性发作频率、哮喘发作住院频率均低于对照组,差异具有统计学意义(P<0.05)。治疗前两组患者的第1秒用力呼气容积(FEV1)/用力肺活量(FVC)、FEV1占预计值百分比(FEV1%)和FEV1比较,差异无统计学意义(P>0.05);治疗后观察组患者的FEV1/FVC、FEV1%和FEV1均高于对照组,差异具有统计学意义(P<0.05)。治疗前两组患者各项生活质量评分比较,差异无统计学意义(P>0.05);治疗后观察组患者各项生活质量评分均低于对照组,差异具有统计学意义(P<0.05)。结论:给予重症哮喘患者支气管热成形术治疗能够显著改善患者临床症状,改善肺功能,提升临床疗效。Objective To analyze the effect of bronchial thermoplasty in the treatment of severe asthma.Methods A selection of 60 patients with severe asthma admitted to Gaozhou People's Hospital from January 2019 to January 2021 were randomly divided into a control group and an observation group,with 30 cases each group.The control group was given conventional treatment,and the observation group was given bronchial thermoforming treatment on the basis of the control group.The clinical effects of the two groups were compared.Results After treatment,the frequency of asthma attacks,the frequency of acute asthma attacks,and the frequency of hospitalizations for asthma attacks in the observation group were lower than those in the control group,the differences were statistically significant(P<0.05);Before treatment,There were no significant differences between in the first second hard work of the two groups expiratory volume occupancy vital capacity ratio(FEV1/FVC),FEV1%and FEV1(P>0.05).After treatment,the FEV1/FVC,FEV1%,and FEV1 of the observation group were higher than those of the control group,and the differences were statistically significant(P<0.05);Before treatment,the difference in quality of life scores between the two groups of patients were no statistically significant(P>0.05).After treatment,the quality of life scores of the observation group were lower than those of the control group,and the differences were statistically significant(P<0.05).Conclusion Bronchial thermoforming treatment for patients with severe asthma can significantly improve patients'clinical symptoms,improve lung function,and enhance clinical efficacy.

关 键 词：重症哮喘 支气管热成形术 二羟丙茶碱 甲泼尼龙琥珀酸钠 复方异丙托溴铵溶液 

分 类 号：R562.25[医药卫生—呼吸系统]