山东省血液中心血液检测不合格情况分析  

Analysis of unqualified blood test in Shandong Blood Center

作　　者：马俊凤 金孟民 呼娜[2] 齐先杰 陈剑锋[4] MA Junfeng;JIN Mengmin;HU Na;QI Xianjie;CHEN Jianfeng(Blood Collecting Department,Blood Center of Shandong Province,Jinan250014,China;Blood Supply Department,Blood Center of Shandong Province,Jinan250014,China;Blood Component Department,Blood Center of Shandong Province,Jinan250014,China;Blood Testing Department,Blood Center of Shandong Province,Jinan250014,China)

机构地区：[1]山东省血液中心体采科,山东济南250014 [2]山东省血液中心供血科,山东济南250014 [3]山东省血液中心成分科,山东济南250014 [4]山东省血液中心检验科,山东济南250014

出　　处：《中国现代医生》2022年第1期21-24,F0003,共5页China Modern Doctor

基　　金：山东省卫生健康政策研究重点课题项目(WZY201952);山东省血液中心科研项目(2020YW08)。

摘　　要：目的了解山东省血液中心无偿献血者实验室检测不合格情况,为进一步提高无偿献血资源利用率提供参考。方法回顾性分析2016年1月至2018年12月山东省血液中心对献血人群检测不合格的资料,按模式不同分为快速检测和实验室检测,分析不合格项目的数据。结果献血前快速检测312780人次,不合格率为5.67%(17736/312780);实验室检测不合格率为1.35%(3942/291799),呈逐年上升趋势,2017与2018年的不合格率间比较,差异有统计学意义(P<0.05);不合格率由高到低依次为ALT(0.43%)、HBsAg(0.29%)、抗-TP(0.27%)、HIV/抗HIV(0.13%)、抗-HCV(0.11%)、异常终止(0.09%)和NAT(0.03%);ALT和异常终止不合格率呈逐年上升趋势,HBsAg和HIV/抗HIV不合格率呈逐年下降趋势,梅毒和核酸检测不合格率呈先升后降趋势,抗-HCV不合格率呈先降后升趋势。结论ALT、抗-TP和HBsAg不合格是导致实验室检测不合格的主要原因,采前快检工作有待进一步改进。Objective To understand the unqualified laboratory test of voluntary blood donors in Shandong Blood Center,and to provide a reference for further improving the utilization rate of voluntary blood donation resources.Methods The data of unqualified blood donors in Shandong Blood Center from January 2016 to December 2018 were retrospectively analyzed.According to different modes,they were divided into rapid detection and laboratory detection,and the data of unqualified items were analyzed.Results A total of 312780 people were detected rapidly before blood donation,and the failure rate was 5.67%(17736/312780).The unqualified rate of laboratory test was 1.35%(3942/291799),which showed an increasing trend year by year.There was a significant difference between 2017 and 2018(P<0.05).The unqualified rates from high to low were ALT(0.43%),HBsAg(0.29%),anti-TP(0.27%),HIV/anti-HIV(0.13%),anti-HCV(0.11%),abnormal termination(0.09%)and NAT(0.03%).The unqualified rates of ALT and abnormal termination increased year by year,the unqualified rates of HBsAg and HIV/anti-HIV decreased year by year,the unqualified rates of syphilis and nucleic acid detection increased first and then decreased,and the unqualified rate of anti-HCV decreased first and then increased.Conclusion The unqualified ALT,anti-TP,and HBsAg are the main causes of unqualified laboratory tests,and the rapid detection before blood collection needs further improvement.

关 键 词：血液筛查 采前快检 血液报废 不合格率 

分 类 号：R446.11[医药卫生—诊断学]