高通透超分子水凝胶:开拓组织再生新思路  

Highly Permeable DNA Supramolecular Hydrogel for Tissue Regeneration

作　　者：张希[1] Xi Zhang(Department of Chemistry,Tsinghua University,Beijing 100084)

机构地区：[1]清华大学化学系,北京100084

出　　处：《高分子学报》2022年第1期1-3,共3页Acta Polymerica Sinica

摘　　要：清华大学刘冬生等用DNA超分子水凝胶负载神经干细胞对脊髓全横断损伤的大鼠进行治疗,使其运动功能显著恢复.研究发现材料的高通透性是干细胞响应自体原位信号调控,实现在损伤部位增殖、分化形成具有完整功能的新神经网络的关键.该项研究为未来的组织再生研究开拓了新思路.By rational design of DNA supramolecular hydrogel with high permeability,Liu and coworkers reported a novel strategy to repair a completely transected spinal cord injury in rats.After the treatment,the rats recover hindlimb function with newly formed neural networks.Therefore,it opens a new avenue for tissue regeneration.

关 键 词：水凝胶 通透性 组织再生 

分 类 号：R318[医药卫生—生物医学工程] TQ427.26[医药卫生—基础医学]