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作 者:许玲[1] 江咏梅[1] 闵玲 钟永林[1] 胡正强[1] XU Ling;JIANG Yongmei;MIN Ling;ZHONG Yongoinglin;HU Zhengqiang(Department of Clinical Laboratory,West China Second Hospital of Sichuan University,Chengdu,Sichuan 610041,China;Department of Obstetrics and Gynecology,West China Second Hospital of Sichuan University,Chengdu,Sichuan 610041,China)
机构地区:[1]四川大学华西第二医院检验科,四川成都610041 [2]四川大学华西第二医院妇产科,四川成都610041
出 处:《国际检验医学杂志》2022年第3期343-346,351,共5页International Journal of Laboratory Medicine
基 金:成都市科技项目(2019-YF05-01178-SN)。
摘 要:目的探讨6~8岁青春发育早期女性外阴阴道的感染特征及其与季节的关系。方法回顾性分析540例6~8岁青春发育早期女性外阴阴道感染状况,分析其不同年龄段、不同季节细菌性阴道病(BV)发生率、炎症发生率、优势菌异常率和假丝酵母菌外阴阴道病(VVC)发生率的差异。结果青春发育早期女性BV发生率、炎症发生率、优势菌异常率、VVC发生率分别为38.52%、16.85%、23.33%、1.11%;BV发生率高于VVC发生率,两者比较差异有统计学意义(P<0.05);优势菌异常中革兰阳性球菌检出102例(80.95%),革兰阴性杆菌检出24例(19.05%),两者比较差异有统计学意义(P<0.05)。不同年龄段BV发生率和炎症发生率差异无统计学意义(P>0.05);6岁组的优势菌异常率高于8岁组,差异有统计学意义(P=0.0127)。秋季的BV发生率和优势菌异常率低于其他季节,差异有统计学意义(P<0.05)。结论青春发育早期女性外阴阴道感染以BV为主;优势菌异常中以革兰阳性球菌检出为主;随着年龄的增长,BV发生率和炎症发生率无明显变化。Objective To investigate the characteristics of vulvovaginal infection in women aged 6-8 in early puberty and their relationship with seasons.Methods A retrospective analysis was made of 540 cases of vulvovaginal infection in women aged 6 to 8 years old in the early stage of puberty.The incidence of bacterial vaginosis(BV),inflammation,abnormal rate of dominant bacteria and candida vulvo-vaginal candidiasis(VVC)in different age groups and seasons were analyzed retrospectively.Results The incidence of BV,inflammation,abnormal dominant bacteria and VVC in women in early puberty were 38.52%,16.85%,23.33%and 1.11%,respectively.The incidence of BV was higher than that of VVC,and the difference was statistically significant(P<0.05).Among the abnormal dominant bacteria,Gram-positive cocci were detected in 102 cases(80.95%),and Gram-negative bacilli were detected in 24 cases(19.05%),the difference was statistically significant(P<0.05).There was no significant difference in the incidence of BV and inflammation in different age groups(P>0.05);the abnormal rate of dominant bacteria in the 6-year-old group was higher than that in the 8-year-old group,and the difference was statistically significant(P=0.0127).The incidence of BV and the abnormal rate of dominant bacteria in autumn were lower than those in other seasons,and the difference was statistically significant(P<0.05).Conclusion The vulvovaginal infection of women in early puberty is mainly BV;the dominant bacterial abnormality is mainly gram-positive coccus.With the increase of age,the incidence of BV and inflammation do not change significantly.
关 键 词:青春发育早期 外阴阴道感染 细菌性阴道病 假丝酵母菌外阴阴道病 季节性
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