人工流产术后继发性不孕原因分析及对女性性激素的影响  

Causes of secondary infertility after induced abortion and its influence on endocrine

作　　者：沈世美 Shen Shimei(Gynecology/Outpatient Family Planning Operation Room,Rugao Hospital of Traditional Chinese Medicine,Rugao 226500,China)

机构地区：[1]如皋市中医院妇科/门诊计生手术室,江苏如皋226500

出　　处：《实用妇科内分泌电子杂志》2022年第1期31-34,共4页Electronic Journal of Practical Gynecological Endocrinology

摘　　要：目的研究分析人工流产术后继发性不孕原因及对女性性激素的影响。方法选取46例行人工流产术后继发性不孕患者为研究组;另选同期40例人工流产术后正常受孕者为对照组。分析继发性不孕影响因素以及对女性性激素的影响。结果两组患者年龄、手术方法、流产次数以及月经不调发生率比较,差异无统计学意义(P>0.05),而宫腔粘连、慢性输卵管炎、卵巢功能障碍、子宫内膜炎、子宫内膜异位症发生率比较,差异有统计学意义(P<0.05)。研究组患者卵泡刺激素(FSH)水平明显高于对照组,而孕酮(P)、促黄体生成素(LH)水平均明显低于对照组,差异有统计学意义(P<0.05),两组泌乳素(PRL)、雌二醇(E_(2))水平比较差异无统计学意义(P>0.05)。研究组患者FSH异常率、FSH/LH升高率分别为19.57%、15.22%,均显著高于对照组的5.00%、2.50%,差异有统计学意义(P<0.05),两组LH、PRL、E2,P异常率比较,差异无统计学意义(P>0.05)。结论临床医生应在实施手术后重视对于女性的定期检查,根据异常采取针对性干预措施,以期改善妊娠结局。Objective To study the causes of secondary infertility after induced abortion and its effect on endocrine.Methods 46 patients with secondary infertility after induced abortion were selected as the study group.40 cases of normal pregnancy after induced abortion were selected as the control group.To analyze the influence factors of secondary infertility and endocrine.Results There were no significant differences in age,surgical method,number of abortion and incidence of irregular menstruation between 2 groups(P>0.05),but there were significant differences in incidence of intrauterine adhesion,chronic salpingitis,ovarian dysfunction,endometritis and endometriosis between 2 groups(P<0.05).The levels of follicle stimulating hormone(FSH)in the study group were significantly higher than those in the control group,while the levels of progesterone(P)and luteinizing hormone(LH)were significantly lower than those in the control group,the differences were statistically significant(P<0.05),while there were no significant differences in the levels of prolactin(PRL)and estradiol(E_(2))between the two groups(P>0.05).The abnormal rate of FSH and increased rate of FSH/LH in the study group were 19.57% and 15.22%,respectively,which were significantly higher than those in the control group(5.00% and 2.50%,P<0.05),but there were no significant differences in abnormal rate of LH,PRL,E2 and P between the two groups(P>0.05).Conclusion Clinicians should pay attention to regular examinations of women after performing operations,and take targeted intervention measures based on indicators in order to improve pregnancy outcomes.

关 键 词：继发性不孕 人工流产术 女性性激素 

分 类 号：R169.42[医药卫生—公共卫生与预防医学] R711.6